Sort   by:  
 Page size 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- cytoplasmic proteins of untreated HCT 116 epithelial cells, 3h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005367 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness - cytoplasmic proteins of untreated HCT 116 epithelial cells, 24h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005373 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness - nuclear proteins of untreated HCT 116 epithelial cells, 24h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005375 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- nuclear proteins of untreated HCT 116 epithelial cells, 3h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005370 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- cytoplasmic proteins of plestatins-2 treated HCT 116 epithelial cells, 24h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005374 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- cytoplasmic proteins of plestatins-2 treated HCT 116 epithelial cells, 3h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005368 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- nuclear proteins of plestatins-2 treated HCT 116 epithelial cells, 3h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005371 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- cytoplasmic proteins of arsenic trioxide treated HCT 116 epithelial cells, 3h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005369 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- nuclear proteins of plestatins-2 treated HCT 116 epithelial cells, 24h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD005376 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
ProteomicsTargeting the Scaffold Protein Plectin by an Organometallic as a Strategy to Inhibit Tumour Invasiveness- whole cell lysate of HCT 116 epithelial cells, plestatins-3 normal pull down 4h
The inability of determining direct molecular targets of metal-based therapeutic agents beyond the platinum class is one of the major bottlenecks in their development. Here, we employ an integrated chemical proteomics and response profiling approach to identify and validate plestatins, based on an o...
ORGANISM(S): Homo sapiens (Human) 
2017-06-02 | PXD005389 | Pride
Ruthenium Response profiling Organometallics Target identification Metallodrugs Chemical proteomics Mechanism of action Plectin 
Sort   by:  
 Page size