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TranscriptomicsRegulatory role of multinucleated giant cells derived from placental CD14+ macrophages: Pathophysiological implications
The role of placental macrophages is largely ignored in the success of pregnancy. We found that CD14+ macrophages purified from at-term placentas spontaneously matured into multinucleated giant cells (MGCs). MGCs lost the expression of CD14 and co-inhibitory molecules, such as Programmed cell Death-...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-38747 | biostudies-arrayexpress
TranscriptomicsPlacenta environment induces the differentiation of macrophages into multinucleated giant cells
A major population of placenta macrophages represented throughout the pregnancy consists of CD14+ macrophages, but their characteristics remain badly understood. Here we purified from placentas at term CD14+ macrophages using positive selection. The phenotyping of CD14+ macrophages performed using f...
ORGANISM(S): Homo sapiens 
2012-12-07 | E-GEOD-29575 | biostudies-arrayexpress
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