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TranscriptomicsFermentation of soy juice by Lactiplantibacillus plantarum confers a yogurt-like texture, flavours and health-promoting metabolites
The aim of the study was to decipher metabolisms responsible (i) for the peculiar adaptation of L. plantarum during soy juice fermentation and (ii) for the release of aroma compounds, amino and short-chain fatty acid, and metabolites with health-promoting properties in soy yogurt. The strategy was t...
ORGANISM(S): Lactiplantibacillus plantarum 
2024-08-18 | E-MTAB-14345 | biostudies-arrayexpress
MetabolomicsMetabolomic signatures discriminate horses with clinical signs of atypical myopathy from healthy co-grazing horses
Atypical myopathy (AM) is a severe rhabdomyolysis syndrome that occurs in grazing horses. Despite the presence of toxins in their blood, all horses from the same pasture are not prone to display clinical signs of AM. The objective of this study was to compare the blood metabolomic profiles of horses...
2021-08-31 | MTBLS2579 | MetaboLights
TranscriptomicsTranscriptional analysis of Lactobacillus delbrueckii subsp. delbrueckii during soy juice fermentation.
The objective of this study was to decipher the metabolism expressed by Lactobacillus delbrueckii subsp. delbrueckii CIRM-BIA865 during soy juice fermentation using transcriptomics. The whole genome was sequenced, assembled and annotated. CIRM-BIA865 was then used to ferment soy juice to produce a s...
ORGANISM(S): Lactobacillus delbrueckii 
2023-05-13 | E-MTAB-12095 | biostudies-arrayexpress
UnknownMitofusin 2 is required to maintain mitochondrial coenzyme Q levels
Not available
S-JCBD-201411100 | bioimages
MetabolomicsUntargeted metabolomics profiling reveals exercise intensity-dependent alterations in Thoroughbred racehorses’ plasma after routine conditioning sessions

Thoroughbred (TB) racehorses are subjected to rigorous conditioning programs involving exercise sessions of various types, distances and intensities. These programs aim to optimize both their physical and mental capabilities, which are essential to achieve maximal performance. Conventional invest...

2024-01-16 | MTBLS8285 | MetaboLights
TranscriptomicsMassive redeployment of PRC1 proteins suppresses tumor formation during Drosophila development
Polycomb group proteins form two main complexes, PRC2 and PRC1, which generally coregulate their target genes. Here, we show that PRC1 components act as neoplastic tumor suppressors independently of PRC2 function. By mapping the distribution of PRC1 components and the histone H3K27me3 mark, we ident...
ORGANISM(S): Drosophila melanogaster 
2016-07-18 | E-GEOD-74080 | biostudies-arrayexpress
ProteomicsQuest for missing proteins in the human spermatozoa: an update
Here, we report work as part of C-HPP initiatives on chromosomes 14 (France) and 2 (Switzerland) aiming to identify missing proteins in ejaculated human spermatozoa using multiple MS-based and antibodies-based validation approaches
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080826 | MassIVE
GenomicsH3K9me3 ChIP-seq on hematopoietic stem cells sorted from mice 1 month after they were irradiated (2Gy total body irradiation = IR) or not (non irradiated = NIR)
We aim at understanding how ionizing radiations (IR) increase the risk of developing myeloid leukemia. We recently showed that IR leads to the derepression of retroelements. We demonstrated that retroelements expression in aged HSCs is regulated by the heterochromatin repressive histone mark H3K9me3...
ORGANISM(S): Mus musculus 
2022-06-24 | E-MTAB-11865 | biostudies-arrayexpress
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
GenomicsThe immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
The immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
PRJNA1020588 | ENA
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