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TranscriptomicsEffects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men
Polyphenolic compounds, such as resveratrol, have recently received widespread interest due to their ability to mimic effects of calorie restriction. The objective of the present study was to gain more insight into the effects of 30 days resveratrol supplementation on adipose tissue morphology and u...
ORGANISM(S): Homo sapiens 
2013-09-25 | E-GEOD-42432 | biostudies-arrayexpress
TranscriptomicsShort-term high fat-feeding results in morphological and metabolic adaptations in the skeletal muscle of C57BL/6J mice
The prevalence of the metabolic syndrome (MS) is rapidly increasing all over the world. Consequently, there is an urgent need for more effective intervention strategies. Both animal and human studies indicate that lipid oversupply to skeletal muscle can result in insulin resistance which is one of t...
ORGANISM(S): Mus musculus 
2007-11-30 | E-GEOD-8524 | biostudies-arrayexpress
TranscriptomicsPolyunsaturated fatty acids acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increases postprandial insulin sensitivity
Dietary fat quality may influence skeletal muscle lipid handling and fat accumulation, thereby modulating insulin sensitivity. Objective: To examine acute effects of meals with various fatty acid (FA) compositions on skeletal muscle FA handling and postprandial insulin sensitivity in obese insulin r...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-31901 | biostudies-arrayexpress
TranscriptomicsSubcutaneous adipose tissue (SAT) gene expression patterns between weight control and regaining weight subjects
Objective: This work aimed at identifying and characterizing differences in subcutaneous adipose tissue (SAT) gene expression patterns between subjects succeeding weight control against subjects regaining weight 6 months after a low calorie diet program. Methods: Weight-reduced obese subjects from 8...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-19494 | biostudies-arrayexpress
TranscriptomicsDrug-induced hepatotoxicity screening in primary mouse hepatocytes, an Omics approach.
Drug-induced hepatotoxicity is a leading cause of attrition of candidate drugs in drug development. Therefore new screening methods are necessary which predict these hazards more accurate and earlier in the drug development process. Of all in vitro hepatotoxicity models, primary human hepatocytes ar...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-33742 | biostudies-arrayexpress
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