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TranscriptomicsTranscriptome analysis of MENXM-bM-^@M-^Qassociated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas
Gonadotroph adenomas comprise 15M-bM-^@M-^S40 % of all pituitary tumors, are usually non-functioning and are often large and invasive at presentation. Surgery is the first-choice treatment, but complete resection is not always achieved, leading to high recurrence rates. As gonadotroph adenomas poorl...
ORGANISM(S): Rattus norvegicus 
2013-07-10 | E-GEOD-23207 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiling of sporadic Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors (PanNETs) account for 1-3% of all neoplasms of the pancreas. Epigenetic changes seem to be the main drivers of PanNET tumorigenesis. Indeed, the most frequent mutated genes in PanNETs are DAXX (Death domain associated protein 6), ATRX (Transcriptional Regulator ATRX)...
ORGANISM(S): Homo sapiens 
2022-11-30 | E-MTAB-11962 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiling of sporadic Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors (PanNETs) account for 1-3% of all neoplasms of the pancreas. Epigenetic changes seem to be the main drivers of PanNET tumorigenesis. Indeed, the most frequent mutated genes in PanNETs are DAXX (Death domain associated protein 6), ATRX (Transcriptional Regulator ATRX)...
ORGANISM(S): Homo sapiens 
2022-11-30 | E-MTAB-11965 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation profiling of sporadic Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors (PanNETs) account for 1-3% of all neoplasms of the pancreas. Epigenetic changes seem to be the main drivers of PanNET tumorigenesis. Indeed, the most frequent mutated genes in PanNETs are DAXX (Death domain associated protein 6), ATRX (Transcriptional Regulator ATRX)...
ORGANISM(S): Homo sapiens 
2020-11-30 | E-MTAB-7924 | biostudies-arrayexpress
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