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Methylation profiling[E-TABM-482] DNA methylome of human spermatozoa
Genome-wide DNA methylation profile of human spermatozoa using the meDIP technique and massively parallel sequencing. DNA methylation is an indispensible epigenetic modification required for regulating the expression of mammalian genomes. Immunoprecipitation-based methods for DNA methylome analysis ...
ORGANISM(S): Homo sapiens 
2011-02-05 | GSE25686 | GEO
TranscriptomicsA high-resolution single-cell multiomic atlas of the human fetal lung - scRNA / GEX / VDJ
We obtained human embryonic and fetal lungs from 5-22 pcw for scRNAseq and scATACseq analysis. To focus on epithelial differentiation and region specialization, we deeply sampled 15, 18, 20 and 22 pcw lungs and separated proximal and distal regions while leaving lungs at 5, 6, 9 and 11 pcw intact. T...
ORGANISM(S): Homo sapiens 
2022-01-27 | E-MTAB-11278 | biostudies-arrayexpress
UnknownA single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breast.
Not available
S-EPMC11018528 | biostudies-literature
TranscriptomicsAcquisition of alveolar fate and differentiation competence by human fetal lung epithelial progenitor cells
Our data show that Wnt and FGF signalling, and the downstream transcription factors NKX2.1 and TFAP2C, promote human alveolar or airway fate respectively. Moreover, we have functionally validated cell-cell interactions in human lung alveolar patterning. We show that Wnt signalling from differentiati...
ORGANISM(S): Homo sapiens 
2022-02-28 | E-MTAB-11435 | biostudies-arrayexpress
TranscriptomicsImmune cells direct epithelial maturation during early human lung development
The adult human lung harbours a significant proportion of immune cells, which are known to play a crucial role in both normal lung homeostasis and pathogenesis. In this work, we collected CD45-enriched human lung cells from 6 to 22 week post conception (pcw) and built a single-cell transcriptome and...
ORGANISM(S): Homo sapiens 
2022-12-09 | E-MTAB-11528 | biostudies-arrayexpress
GenomicsHomo sapiens
[E-TABM-482] DNA methylome of human spermatozoa
PRJNA135835 | ENA
TranscriptomicsRNA-seq of liver tissue and liver cancer cell lines
This dataset has been designed to test whether codons in mRNAs and anticodons in tRNAs vary in order to maximize translation in specific cellular conditions in mammals. Prokaryotes and simple unicellular eukaryotes optimize their translational rates by adjusting the codons in the protein-coding tran...
ORGANISM(S): human 
2016-04-18 | E-MTAB-4052 | biostudies-arrayexpress
GenomicsPol III ChIP-seq of liver cancer cell lines
This dataset has been designed to test whether codons in mRNAs and anticodons in tRNAs vary in order to maximize translation in specific cellular conditions in mammals. Prokaryotes and simple unicellular eukaryotes optimize their translational rates by adjusting the codons in the protein-coding tran...
ORGANISM(S): human 
2016-04-18 | E-MTAB-4046 | biostudies-arrayexpress
UnknownA spatial human thymus cell atlas mapped to a continuous tissue axis.
Not available
S-EPMC11578893 | biostudies-literature
UnknownNeurology-related protein biomarkers are associated with cognitive ability and brain volume in older age.
Not available
S-EPMC7010796 | biostudies-literature
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