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TranscriptomicsMARIS: Method for Analyzing RNA following Intracellular Sorting [RNA-seq]
We've developed a new Method to Analyze RNA following Intracellular Sorting (MARIS) allowing us to carry out gene expression studies on cells sorted based on intracellular immunoflourescence. The purpose of this study is to determine the degree of bias that MARIS introduces on gene expression. We re...
ORGANISM(S): Homo sapiens 
2014-01-17 | E-GEOD-54178 | biostudies-arrayexpress
TranscriptomicsMARIS: Method for Analyzing RNA following Intracellular Sorting [array]
We've developed a new Method to Analyze RNA following Intracellular Sorting (MARIS) allowing us to carry out gene expression studies on cells sorted based on intracellular immunoflourescence. The purpose of this study is to determine the degree of bias that MARIS introduces on gene expression. We re...
ORGANISM(S): Homo sapiens 
2014-01-13 | E-GEOD-53941 | biostudies-arrayexpress
TranscriptomicsRNA-seq comparison: before/after MARIS protocol and library construction technique test
The aim of this experiment was to determine the amount of RNA-seq signal degradation that results from MARIS and to test how well 4 different RNA-seq library construction techniques perform on partially degraded RNA.
ORGANISM(S): Homo sapiens 
2015-03-19 | E-MTAB-3424 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Ins+, Ucn3+/- cell populations within developmental mouse islets using MARIS
The aim of this experiment was to observe the transcriptional profile of individual populations of cells in mouse islets throughout development. MARIS was used to isolate Ins+ islet cells at E18.5 and P13, and further separate Ucn3- and Ucn3+ populations at the transition point P4 and P5.
ORGANISM(S): Mus musculus 
2015-03-17 | E-MTAB-3418 | biostudies-arrayexpress
TranscriptomicsDifferentiated human stem cells resemble fetal, not adult, β cells
Human pluripotent stem cells (hPSCs) have the potential to generate any human cell type, and one widely recognized goal is to make pancreatic β cells. To this end, comparisons between differentiated cell types produced in vitro and their in vivo counterparts are essential to validate hPSC-derived c...
ORGANISM(S): Homo sapiens 
2014-03-25 | E-GEOD-56130 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Pdx1+ mouse Islet during development
The aim of this experiment was to observe the transcriptional profile of mouse islets during development (at timepoints E18.5, P10, Adult). RNA-seq was performed on the same RNA that was used for an earlier microarray. No MARIS sorting.
ORGANISM(S): Mus musculus 
2015-03-16 | E-MTAB-3417 | biostudies-arrayexpress
UnknownA G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma.
Not available
S-EPMC8069650 | biostudies-literature
UnknownNatural history of KBG syndrome in a large European cohort.
Not available
S-EPMC9759332 | biostudies-literature
UnknownGain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling.
Not available
S-EPMC4004585 | biostudies-literature
UnknownExtreme phenotypic heterogeneity in non-expansion spinocerebellar ataxias.
Not available
S-EPMC10357418 | biostudies-literature
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