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UnknownAlterations in DNA Damage Response and Repair Genes as Potential Marker of Clinical Benefit From PD-1/PD-L1 Blockade in Advanced Urothelial Cancers.
Not available
S-EPMC6366295 | biostudies-literature
UnknownPolycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F.
Not available
S-EPMC4979103 | biostudies-literature
MetabolomicsIntegrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma were characterized using multi-platform metabolic phenotyping with Nuclear Magnetic Resonance (NMR) spectroscopy and liquid chromatography-mass spectrometry (LC-MS). Quantitative mea...
2021-01-29 | MTBLS2014 | MetaboLights
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
GenomicsOSKM factors cooperatively engage chromatin to initiate reprogramming
Reprogramming cells from one fate to another, using transcription factors, generates cells for research and potential therapy, yet little is known about the initial engagement of reprogramming factors with the genome. We mapped the interactions between Oct4, Sox2, Klf4, and c-Myc (OSKM) and the hum...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36570 | biostudies-arrayexpress
UnknownGenotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.
Not available
S-EPMC3158597 | biostudies-literature
UnknownChoosing wisely: the American College of Rheumatology's Top 5 list of things physicians and patients should question.
Not available
S-EPMC4106486 | biostudies-literature
GenomicsEpigenome and transcriptome of naive pluripotent mouse embryonic stem (ES) cells cultured in 2i serum-free medium
This study describes the epigenetic and transcriptome profiling of mouse ES cells cultures in 2i serum-free medium. The proteins for which ChIP-Seq profiles were generated in these cells, as well as for cells grown in serum conditions, include H3K4me3, H3K36me3, H3K27me3, H3K9me3, Suz12 and Ezh2. A...
ORGANISM(S): Mus musculus 
2012-04-26 | E-GEOD-23943 | biostudies-arrayexpress
UnknownRandomized phase II study of carboplatin and paclitaxel with either linifanib or placebo for advanced nonsquamous non-small-cell lung cancer.
Not available
S-EPMC5478045 | biostudies-literature
UnknownRheumatoid arthritis disease activity measures: American College of Rheumatology recommendations for use in clinical practice.
Not available
S-EPMC4028066 | biostudies-literature
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