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GenomicsImpact of Tcf1 and Lef1 deficiency on histone marks and Tcf1 binding in CD8 T cells
Comparison of epigenome and Tcf1 occupancy between control and Tcf1/Lef1-deficient CD8 T cells Control mice or those are deficient for Tcf1 and Lef1 transcription factors (deleted by CD4-Cre) were used to isolate thymocytes. The thymocytes were surface-stained to identify TCRbeta high, CD69–, CD24...
ORGANISM(S): Mus musculus 
2016-02-12 | E-GEOD-73239 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis homeodomain 2 trichomes
Transcriptional profiling of isolated homeodomain 2 (hd2) trichomes
ORGANISM(S): Arabidopsis thaliana 
2009-02-04 | E-MEXP-2022 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis ecotype Columbia trichomes
Leaf trichomes of Columbia isolated using associated protocol.
ORGANISM(S): Arabidopsis thaliana 
2009-02-03 | E-MEXP-2008 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis gl3-sst sim trichomes
Transcriptional profiling of isolated gl3-sst sim trichomes.
ORGANISM(S): Arabidopsis thaliana 
2009-02-04 | E-MEXP-2013 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis ecotype Columbia leaf tissue processed for trichome isolation
Transcriptional profiling of leaf tissue processed for trichome isolation.
ORGANISM(S): Arabidopsis thaliana 
2009-02-04 | E-MEXP-2014 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis gl3-sst trichome cells
Transcriptional profiling of isolated gl3-sst trichome cells.
ORGANISM(S): Arabidopsis thaliana 
2009-02-03 | E-MEXP-2009 | biostudies-arrayexpress
TranscriptomicsPreprocessed reduced representation bisulfite sequencing (RRBS) data from 173 human umbilical cord blood samples, collected for a study on associations between perinatal DNA methylation marks and progression to type 1 diabetes by age 15
The samples were collected from the participants of the Finnish Diabetes Prediction and Prevention (DIPP) Study, born between 1995 and 2006. DIPP is a prospective follow-up cohort of children with a moderate or high risk of type 1 diabetes, based on the HLA-DR-DQ genotype. Islet cell autoantibodies ...
ORGANISM(S): Homo sapiens 
2022-06-06 | E-MTAB-10530 | biostudies-arrayexpress
Transcriptomicsm1A marks translation initiation sites in human and mouse messenger RNA [Sequencing]
We developed a novel approach, m1A-seq, for high-resolution mapping of the transcriptome-wide m1A landscape, based on antibody-mediated capture followed by massively parallel sequencing Identification of m1A modified sequences in human, mouse and yeast cell lines
ORGANISM(S): Homo sapiens 
2016-02-10 | E-GEOD-70485 | biostudies-arrayexpress
GenomicsGenome-wide nucleosome positioning during embryonic stem cell development [ChIP-Seq]
We determined genome-wide nucleosome occupancy in mouse embryonic stem cells and their neural progenitor and embryonic fibroblast counterparts to assess features associated with nucleosome positioning during lineage commitment. Cell type and protein specific binding preferences of transcription fact...
ORGANISM(S): Mus musculus 
2012-10-21 | E-GEOD-40951 | biostudies-arrayexpress
MetabolomicsOperation of a TCA cycle subnetwork in the mammalian nucleus

Nucleic acid and histone modifications critically depend on tricarboxylic acid (TCA) cycle for substrates and co-factors. Although a few TCA cycle enzymes have been reported in the nucleus, the corresponding pathways are considered to operate in mitochondria. Here, we show that a part of the...

2022-06-15 | MTBLS2235 | MetaboLights
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