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TranscriptomicsRole of σ54 in the regulation of genes involved in biogenesis of type I and type IV pili in Xylella fastidiosa
The phytopathogen Xylella fastidiosa produces two classes of pili, long type IV pili and short type I pili, which are involved in motility and adhesion. In this work, we have investigated the role of σ54 factor and its involvement in the regulation of fimbrial biogenesis in X. fastidiosa. An rpoN n...
ORGANISM(S): Xylella fastidiosa 
2010-06-25 | E-GEOD-8097 | biostudies-arrayexpress
GenomicsGenome wide targeting of the epigenetic regulatory protein CTCF to gene promoters by the transcription factor TFII-I [ChIP-Seq]
Analysis of CTCF binding in Wehi-231 with TFII-I knockdown compare to Wehi-231 wt. ChIP experiment of CTCF in Wehi-231-CT and Wehi-231-shTFII-I
ORGANISM(S): Mus musculus 
2014-08-29 | E-GEOD-60917 | biostudies-arrayexpress
ProteomicsUsing SWATH-MS to unveil hCSCs response to hCM I/R injury paracrine factors
Human Cardiac/Progenitod Stem Cells (hCSCs) transplantation is arising as a novel therapy option for acute myocardial infarction (AMI) patients. The majority of the studies reported point to paracrine signaling as the main effector in hCSCs activation and regenerative capacity. However, the mechanis...
ORGANISM(S): Homo sapiens (Human) 
2019-09-25 | PXD011998 | Pride
Myocardial ischemia/reperfusion injury Human cardiac stem cells Acute myocardial infarctio Human induced pluripotent stem cell derived cardiomyocytes. 
MetabolomicsMetabolite profile data of grapevine plants with brown wood streaking and grapevine leaf stripe (esca complex disease) symptoms

Leaf samples were obtained from Vitis vinifera ‘Malvasia Fina’ plants with well-characterized esca complex disease symptoms (n = 18) and from healthy uninfected plants (n = 6). Leaves from diseased plants were divided into three groups: asymptomatic (ASY), chlorotic (SY1), and scorched leaves (SY...

2021-11-21 | MTBLS353 | MetaboLights
UnknownEssential and Non-essential Trace Elements in Milks and Plant-Based Drinks.
Not available
S-EPMC9439980 | biostudies-literature
UnknownSynthesis of the ABC Ring of Calyciphylline A-Type Alkaloids by a Stereocontrolled Aldol Cyclization: Formal Synthesis of (±)-Himalensine A.
Not available
S-EPMC9881646 | biostudies-literature
ProteomicsHuman myocardial ischemia/reperfusion injury model to study cardiac stem cells activation and regeneration mechanisms
The importance of regenerative potential of cardiac stem/progenitor cells (CSCs) after acute myocardial infarction (AMI) has been emphasized in the last decade. Several studies have demonstrated that this cell population has a relevant role in myocardial repair, supported by the establishment of a p...
ORGANISM(S): Homo sapiens (Human) 
2019-02-18 | PXD008156 | Pride
Cardiac stem/progenitor cells  acute myocardial infarction  ischemia/reperfusion injury 
MetabolomicsPathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
TranscriptomicsThe choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease
Alzheimer’s disease (AD) is a neurodegenerative disease characterized by a marked decline in cognition and memory formation. Increasing evidence highlights the essential role of neuroinflammatory and immune-related molecules, namely the ones that are produced at the brain barriers, on brain immune...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-66598 | biostudies-arrayexpress
UnknownSalt Stress Tolerance in Casuarina glauca: Insights from the Branchlets Transcriptome.
Not available
S-EPMC9658546 | biostudies-literature
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