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TranscriptomicsDifferentiation of human fetal multipotential neural progenitor cells to astrocytes reveals susceptibility factors for JC Virus
Viral infections of the CNS are of increasing concern, especially among immunocompromised populations. Rodent models are often inappropriate for studies of CNS infection, as many viruses, including JC Virus (JCV) and HIV, cannot replicate in rodent cells. Consequently, human fetal brain-derived mult...
ORGANISM(S): Homo sapiens 
2013-04-09 | E-GEOD-43794 | biostudies-arrayexpress
TranscriptomicsClonal Immortalized Human Glial Cell Lines Support Varying Levels of JC Virus Infection due to Differences in Cellular Gene Expression
JC virus (JCV) is a ubiquitous human polyomavirus that causes the demyelinating disease Progressive Multifocal Leukoencephalopathy (PML). JCV replicates in limited cell types in culture, predominantly in human glial cells. Thus, productive JCV infection is an indicator of the host cell transcription...
ORGANISM(S): Homo sapiens 
2013-10-17 | E-GEOD-45639 | biostudies-arrayexpress
UnknownAlterations in Excitatory and Inhibitory Synaptic Development Within the Mesolimbic Dopamine Pathway in a Mouse Model of Prenatal Drug Exposure.
Not available
S-EPMC8710665 | biostudies-literature
TranscriptomicsPriming defense genes and metabolites in hybrid poplar by the green leaf volatile cis-3-hexenyl acetate
• Herbivore-induced plant volatiles (HIPVs), in addition to attracting natural enemies of herbivores, can serve a signaling function within plants by acting as wound signals that induce or prime defenses. However, particularly in woody plants, which compounds within HIPV blends are capable of act...
ORGANISM(S): Populus x canadensis 
2010-05-25 | E-GEOD-11955 | biostudies-arrayexpress
UnknownEpithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma.
Not available
S-EPMC6882813 | biostudies-literature
UnknownEffect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial.
Not available
S-EPMC12055926 | biostudies-literature
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
UnknownTranslational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis.
Not available
S-EPMC7494911 | biostudies-literature
UnknownEthical considerations in conducting surgical research in severe complicated intra-abdominal sepsis.
Not available
S-EPMC6683332 | biostudies-literature
UnknownStratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States.
Not available
S-EPMC11962403 | biostudies-literature
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