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ProteomicsMetabolic control of DNA methylation and imprinted gene expression in naive pluripotent cells
Naive pluripotent epiblast cells of the preimplantation murine embryo and their in vitro counterpart, embryonic stem (ES) cells, have the capacity to give rise to all cells of the adult. Such developmental plasticity is associated with global genome hypomethylation. It is unclear whether genome meth...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-26 | PXD020385 | Pride
Dna methylation Tet Es Dnmts 
ProteomicsFeeder-free culture of naive human PSCs preserving embryonic, extraembryonic and blastoid potential
Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organise into blastocyst-like structures called blastoids. Naive hPSCs maintenance commonly relies on mouse...
ORGANISM(S): Bos taurus (Bovine) Rattus norvegicus (Rat) 
2025-12-22 | PXD059820 | Pride
ProteomicsFeeder-free culture of naive human PSCs preserving embryonic, extraembryonic and blastoid potential
Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organise into blastocyst-like structures called blastoids. Naive hPSCs maintenance commonly relies on mouse...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-22 | PXD072053 | Pride
TranscriptomicsTranscriptional profiling of LIF stimulation in mouse embryonic stem cells
Stat3+/+ and -/- ES cells were cultured in defined conditions and exposed to leukemia inhibitory factor (LIF) in a 24h timecourse to identify Stat3-independent targets of the self-renewal response to LIF signaling.
ORGANISM(S): Mus musculus 
2013-08-01 | E-MTAB-1796 | biostudies-arrayexpress
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