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Type 1 diabetes is an autoimmune disease in which insulin-secreting β cells of the pancreatic islets are selectively destroyed. CD8 T cells are regarded as critical players in mediating β cell destruction and as a result, considerable effort has been expended to define CD8 T cell behaviour in this d...
ORGANISM(S): Homo sapiens 
Cytolytic activity by CD8+ cytotoxic T lymphocytes (CTL) is a powerful tactic in the elimination of intracellular pathogens and tumor cells. The destructive capacity of CTL is progressively dampened during chronic infection - yet the environmental cues and molecular pathways controlling immune “exha...
ORGANISM(S): Mus musculus 
Sweat is emerging as a prominent biosource for real-time human performance monitoring applications. Although promising, sources of variability must be identified to truly utilize sweat for biomarker applications. In this proof-of-concept study, a targeted metabolomics method was applied to sweat col...
2021-03-15 | MTBLS2427 | MetaboLights
Data from ProteomeXchange, PXD ID: PXD000975. File: F010311.mgf. Published as part of Proteomics. 2015 Apr 29 . From the Abstract: {{i}} Casein kinase 2 (CK2) is a protein kinase that phosphorylates a plethora of cellular target proteins involved in processes including DNA repair, cell cycle contro...
ORGANISM(S): Ostreococcus_tauri 
S. Typhimurium SL1344 was exposed to the minimum inhibitory concentration of triclosan and the transcriptomic response analysed.
ORGANISM(S): Salmonella enterica 
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