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ProteomicsMetaproteomic profiling of a granule-forming Ca. Accumulibacter enrichment
Extracellular proteins play key roles in microbial biofilm and aggregate formation, yet remain poorly understood. Using two advanced metaproteomic techniques, this study identified and classified 387 extracellular proteins potentially involved in aggregate formation, including filamentous and cell s...
ORGANISM(S): Candidatus Accumulibacter phosphatis 
2025-02-21 | PXD057220 | Pride
Shotgun proteomics Ca. accumulibacter phosphatis Granular biofilm Secretome 
MetabolomicsA data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity
The mechanisms responsible for weight loss-induced improvement in insulin sensitivity are partially understood. Greater insight can now be achieved through deep phenotyping and data integration. Here, we used an integrative approach to investigate associations between changes in insulin sensitivity ...
2021-02-11 | MTBLS653 | MetaboLights
ProteomicsA multiomics study on the metabolism of Ca. Accumulibacter phosphatis
A metabolomics and whole cell lysate shotgun proteomics study was performed to investigate the glycolytic modes in Ca. Accumulibacter phosphatis.
ORGANISM(S): Candidatus Accumulibacter phosphatis 
2024-10-28 | PXD048326 | Pride
Ca. accumulibacter phosphatis Shotgun proteomics Glycolysis 
ProteomicsCa. Lokiarchaeum ossiferum B35 proteomic analysis
Proteomic expression analysis of Ca. Lokiarchaeum ossiferum, strain B35, grown using casein hydrolysate as the main carbon source under anaerobic conditions
ORGANISM(S): Candidatus Lokiarchaeum sp. B-35 
2025-03-14 | PXD059733 | Pride
Ca. lokiarchaeum ossiferum 
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
MetabolomicsUntargeted In Silico Compound Classification - A Novel Metabolomics Method to Assess the Chemodiversity in Bryophytes

In plant ecology, biochemical analyses of bryophytes and vascular plants are often conducted on dried herbarium specimen as species typically grow in distant and inaccessible locations. Here, we present an automated in silico compound classification framework to annotate metabolites using an unta...

2026-01-30 | MTBLS851 | MetaboLights
TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
MetabolomicsGrowth Substrate and Prophage Induction Collectively Influence Metabolite and Lipid Profiles in a Marine Bacterium

Bacterial growth substrates influence a variety of biological functions, including the biosynthesis and regulation of lipid intermediates. The extent of this rewiring is not well understood nor has it been considered in the context of virally-infected cells. Here, we use a one-host-two-temperate ...

2022-08-04 | MTBLS5345 | MetaboLights
TranscriptomicsAn interferon-response induced by tumor-stroma interaction in a subset of human breast cancers
This SuperSeries is composed of the following subset Series: GSE7260: epithelial-mesenchymal interaction of the breast GSE7263: Effect of heterotypic interaction between breast cancer cell line MDA-MB231 and CCL-171 fibroblast Refer to individual Series
ORGANISM(S): Homo sapiens 
2007-11-13 | E-GEOD-7264 | biostudies-arrayexpress
Transcriptomicsepithelial-mesenchymal interaction of the breast
These 95 arrays are the basis for Figure 2 of our manuscript "An interferon-response induced by tumor-stroma interaction in a subset of human breast cancers". Abstract:Background Communication between different cell types is a cardinal feature of multi-cellular organisms and perturbations ...
ORGANISM(S): Homo sapiens 
2007-11-13 | E-GEOD-7260 | biostudies-arrayexpress
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