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TranscriptomicsAntioxidants Accelerate Lung Cancer Progression in Mice
Antioxidants are widely used to protect cells from damage induced by reactive oxygen species (ROS). The concept that antioxidants can help fight cancer is deeply rooted in the general population, promoted by the food supplement industry, and supported by some scientific studies. However, clinical tr...
ORGANISM(S): Mus musculus 
2014-01-31 | E-GEOD-52594 | biostudies-arrayexpress
MetabolomicsImproving the Screening Analysis of Pesticide Metabolites in Human Biomonitoring by Combining High-Throughput In Vitro Incubation and Automated LC-HRMS Data Processing
There is a current need to monitor human exposure to a large number of pesticides and other chemicals of emerging concern (CECs). This requires screening analysis with high confidence for these compounds and their metabolites in complex matrices, which is hampered by the fact that no reference stand...
2022-01-17 | MTBLS2402 | MetaboLights
TranscriptomicsThe systematic shortening of 3’ UTRs has limited influence on the relative change in protein abundance in proliferating cells
Alternative polyadenylation is an important cellular mechanism that enables generation of mRNA isoforms that differ in their 3' untranslated regions (3' UTRs) and consequently in their susceptibility to miRNA and RNA binding protein mediated regulation. A dramatic change in polyadenylation site usa...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-54950 | biostudies-arrayexpress
UnknownTriclosan changes community composition and selects for specific bacterial taxa in marine periphyton biofilms in low nanomolar concentrations.
Not available
S-EPMC7427700 | biostudies-literature
ProteomicsStructure of an essential inner membrane protein-LPS complex identifies a novel anti-microbial peptide
Lipopolysaccharide (LPS) resides in the outer membrane (OM) of Gram-negative bacteria where it is responsible for barrier function and immune modulation. LPS is the target of polymyxins, last-resort antibiotics whose clinical use is threatened by increasing resistance. Steps in LPS biogenesis are ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2019-05-08 | MSV000083754 | MassIVE
MetabolomicsA data set of 255000 randomly selected and manually classified extracted ion chromatograms for evaluation of peak detection methods

Nontargeted mass spectrometry (MS) has become an important method over the last years in the fields of metabolomics and environmental research. While more and more algorithms and workflows become available to process a large number of data sets nontargeted, there still exist few manually evaluate...

2020-05-26 | MTBLS1455 | MetaboLights
UnknownImproving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters.
Not available
S-EPMC10284706 | biostudies-literature
UnknownGenomewide Association Study of Severe Covid-19 with Respiratory Failure.
Not available
S-EPMC7315890 | biostudies-literature
GenomicsBIH COVID-19 airway single-cell data access committee.
Data Access Committee EGAC00001001627
EGAC00001001627 | EGA
TranscriptomicsDetection of mutant NPM1 mRNA in acute myeloid leukemia (AML) using custom gene expression arrays [Training cohort]
Abstract Mutations in the gene encoding nucleophosmin (NPM1) carry prognostic value for patients with acute myeloid leukemia (AML). Various techniques are currently being used to detect these mutations in routine molecular diagnostics. Incorporation of accurate NPM1 mutation detection on a gene expr...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-42194 | biostudies-arrayexpress
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