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TranscriptomicsAnalysis of human neurotrophins and receptors in bone marrow stromal cells (BMSC) treated with NGF or BDNF
BMSC gene expression profiling was completed to examine the baseline neurotrophin and receptor gene expression in BMSC and to evaulate changes in gene expression in response to NGF or BDNF stimulation In the study, primary BMSC were treated with recombinant human NGF or BDNF for 24 hours. Following...
ORGANISM(S): Homo sapiens 
2010-05-01 | E-GEOD-18537 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Inhba flox/- Inhbb-/- Amhr2cre/+ activin-deficient granulosa cells vs. wild type
Compares activin deficient granulosa cells (Inhba flox/-; Inhbb-/-; Amhr2cre/+) to wild type granulosa cells Experiment Overall Design: Three replicate wild type granulosa cell samples compared to 2 activin-deficient granulosa cell samples. Each replicate is derived from 2-3 females.
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7150 | biostudies-arrayexpress
TranscriptomicsIN VITRO ASSESSMENT OF ACUTE EXPOSURE OF THS2.2 AEROSOL ON ORGANOTYPIC ACUTE HUMAN BRONCHIAL TISSUE CULTURES
In vitro toxicology approaches have evolved, from a focus on the molecular changes within a cell to understanding of toxicity-related mechanisms that simulate the in vivo environment. The recent development of three dimensional (3-D) organotypic nasal epithelial culture models offer a physiologicall...
ORGANISM(S): Homo sapiens 
2016-12-01 | E-MTAB-5179 | biostudies-arrayexpress
UnknownMolecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.
Not available
S-EPMC6369924 | biostudies-literature
Transcriptomicsaffy_ath_2012_05-Arabidopsis Ubiquitin-Like Proteases characterization
affy_ath_2012_05 - affy_ath_2012_05 - The main objective is to determinate the influence of Ubiquitin-Like Proteases in plant transcriptional modulation. The experiment will also allow us to find what transcriptional cues are particularly affected in the mutants relatively to wild-type.-Seeds were s...
ORGANISM(S): Arabidopsis thaliana 
2013-09-01 | E-GEOD-43883 | biostudies-arrayexpress
TranscriptomicsA systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures (miRNA data)
This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette. Human organotypic bronchial epithelial cultures were exposed to an aerosol from THS2.2 (a candidate modified-risk to...
ORGANISM(S): Homo sapiens 
2016-12-15 | E-MTAB-5318 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression profiling of MIHA cells transfected with C-terminal truncated HBx mutants
To compare the differentially expressed transcriptomes between MIHA cells transfected with empty vector control or different C-terminal truncated HBx mutants (14 or 35 amino acid carboxyl-terminal truncation - i.e. d14 and d35) mRNA profiles of MIHA cells stably overexpressing empty vector control o...
ORGANISM(S): Homo sapiens 
2016-08-02 | E-GEOD-71993 | biostudies-arrayexpress
Transcriptomicsaffy_med_2011_06-Analysis of the Medicago noot mutant
affy_med_2011_06 - affy_med_2011_06 - Legume plants establish a symbiotic interaction with soil bacteria called rhizobia. A complex molecular dialogue between the two partners is necessary for the successful infection and organogenesis processes that will ultimately result in the formation of a nitr...
ORGANISM(S): Medicago truncatula 
2012-05-31 | E-GEOD-36558 | biostudies-arrayexpress
Transcriptomicsaffy_rnai_cadpoplars: Transcriptome analysis of RNAi-CAD transgenic poplars
affy_rnai_cadpoplar - affy_rnai_cadpoplars - This experiment aims to characterize global gene expression in young xylem of transgenic RNAi-CAD poplars in comparison to WT poplars. Cinnamyl Alcohol Dehydrogenase (CAD) is the final enzyme involved in the monolignol biosynthesis pathway. Transgenic pop...
ORGANISM(S): Populus tremula x Populus alba 
2011-09-29 | E-GEOD-27063 | biostudies-arrayexpress
TranscriptomicsCharacterisation of the mouse megakaryocyte transcriptome
This study aims to identify all genes expressed in primary mouse megakaryocytes Keywords: Megakaryocyte, SAGE, transcriptome analysis Mouse megakaryocytes were grown in vitro from bone marrow progenitors. Mature, polyploid (approximately 95% 64n and 128n) differentiated megakaryocytes were used to ...
ORGANISM(S): Mus musculus 
2007-02-02 | E-GEOD-6940 | biostudies-arrayexpress
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