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TranscriptomicsTNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
Classical Hodgkin lymphoma (cHL) is one of the most common malignant lymphomas. It is characterized by the presence of rare Hodgkin and Reed/Sternberg (HRS) cells embedded in an extensive inflammatory infiltrate. Constitutive activation of nuclear factor-kappaB (NF-kappaB) in HRS cells which transcr...
ORGANISM(S): Homo sapiens 
2010-05-20 | E-GEOD-15264 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiles across different brain regions in healthy mice
Genome wide DNA methylation profiling of normal and disease samples from different mice models. A custom Illumina Golden Gate DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 800 CpGs. Bisulphite converted DNA from the 66 samples were hybridised to the Illumi...
ORGANISM(S): Mus musculus 
2013-09-16 | E-GEOD-47038 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiles across different brain regions in Alzheimer disease mice models
Genome wide DNA methylation profiling of normal and disease samples from different mice models. A custom Illumina Golden Gate DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 800 CpGs. Bisulphite converted DNA from the 35 samples were hybridised to the Illumi...
ORGANISM(S): Mus musculus 
2013-09-16 | E-GEOD-47036 | biostudies-arrayexpress
UnknownDiscovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies.
Not available
S-EPMC5458547 | biostudies-literature
UnknownEpigenetic-based differentiation therapy for Acute Myeloid Leukemia.
Not available
S-EPMC11219871 | biostudies-literature
UnknownWhole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.
Not available
S-EPMC4381520 | biostudies-literature
UnknownChromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma.
Not available
S-EPMC7545147 | biostudies-literature
UnknownCharacteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain.
Not available
S-EPMC7399713 | biostudies-literature
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