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MetabolomicsCascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
TranscriptomicsDistinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human]
TDP-43, FUS, and TAF15 are implicated in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. We integrate CLIP-seq and RNA Bind-N-Seq technologies to discover that TAF15 binds to ~4,900 RNAs enriched for GGUA motifs. In the mouse brain, TAF15 and FUS, but not TDP-43, exhibit strikingly ...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-77702 | biostudies-arrayexpress
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.

Background

Acute diverticulitis is a common condition that can be a surgical emergency. Its prevalence is increasing worldwide, however optimal management remains unclear. This study aimed to determine current practice and short-term outcomes globally.

Methods

A prospective, internati...
S-EPMC12512976 | biostudies-literature
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