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TranscriptomicsmRNA transcription profiling by RNAseq of Drosophila melanogaster in stress conditions
Explorative analysis of transcriptional changes in the brains of adult flies.
ORGANISM(S): Drosophila melanogaster 
2020-03-16 | E-MTAB-7952 | biostudies-arrayexpress
MetabolomicsUntargeted LC-MS metabolomic studies of Asteraceae species to discover inhibitors of Leishmania major dihydroorotate dehydrogenase

INTRODUCTION: Interesting data about the family Asteraceae as a new source of Leishmania major dihydroorotate dehydrogenase (LmDHODH) inhibitors are presented. This key macromolecular target for parasites causing neglected diseases catalyzes the fourth reaction of the de novo pyr...

2019-10-14 | MTBLS722 | MetaboLights
TranscriptomicsBiology of human melanoma
In normal skin, interactions between melanocytes and keratinocytes, and between melanocytes and the basal membrane are functionally relevant for maintenance of homeostasis and epidermal melanin unit whose deregulation may trigger a continuous proliferation of the melanocytes. In order to further elu...
ORGANISM(S): Homo sapiens 
2011-10-31 | E-GEOD-17275 | biostudies-arrayexpress
UnknownWeek 240 Efficacy and Safety of Fostemsavir Plus Optimized Background Therapy in Heavily Treatment-Experienced Adults with HIV-1.
Not available
S-EPMC10581994 | biostudies-literature
TranscriptomicsRNA-sequencing of human umbilical cord-derived MSC (UCX) in normoxia and hypoxia
Human umbilical cord matrix-derived mesenchymal stromal cells (UCM-MSC) are advantageous since can be easily obtained and display special interest as universal and feasible add-on therapy for myocardial infarction (MI). In this study, UCM-MSC from two umbilical cords, UC-A and UC-B, were transplante...
ORGANISM(S): Homo sapiens 
2021-01-07 | E-MTAB-9978 | biostudies-arrayexpress
UnknownNutritional counselling in adults promoting adherence to the Mediterranean diet as adjuvant in the treatment of major depressive disorder (INDEPT): a randomized open controlled trial study protocol.
Not available
S-EPMC10074649 | biostudies-literature
TranscriptomicsSignaling Pathways Deferentially Affect RNA Polymerase II Initiation, Pausing, and Elongation in Human Cells: TNF-alpha dependent signaling in AC16 cells
We used Global Run-on and Sequencing (GRO-seq) to measure the rate of transcription elongation by RNA polymerase II (Pol II) following gene activation. We observed that Pol II elongation rates can vary as much as 4-fold at different genomic loci and in response to two distinct cellular signaling pa...
ORGANISM(S): Homo sapiens 
2013-04-10 | E-GEOD-41323 | biostudies-arrayexpress
UnknownThe 2019 Rio Grande birth cohort: profile of a Brazilian 5-year study on mental health conditions.
Not available
S-EPMC12531462 | biostudies-literature
ProteomicsRedox control of antibiotic biosynthesis in Streptomyces formicae
Streptomyces bacteria make diverse specialised metabolites that form the basis of ~55% of clinically used antibiotics. Despite this, only 3% of their encoded specialised metabolites have been matched to molecules and understanding how their biosynthesis is controlled is essential to fully exploit th...
ORGANISM(S): Streptomyces formicae 
2025-08-05 | PXD061171 | Pride
Proteomics Antibiotic biosynthesis Redox Formicamycins Regulation 
UnknownStoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort.
Not available
S-EPMC10549897 | biostudies-literature
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