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TranscriptomicsGene expression profiling of Acute Myeloid Leukemia (AML) samples
The aim was to analyze the expression of genes in cytogenetically distinct cases of AML. We used total RNA obtained from 6 AML samples, consisting of 3 cytogenetically distinct subtypes, to establish the expression levels of 27,868 individual human genes. Expression data from the ABI Human Genome Su...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-34722 | biostudies-arrayexpress
GenomicsLoss of imprinting at the CTCF binding sites in the DLK1-DIO3 domain reactivates microRNA expression in acute promyelocytic leukaemia
We report the DNA-methylation profiling of 10 regions selected from the DLK1-DIO3 domain on chromosome 14q32 in BM/PB samples from patients with acute promyelocytic leukaemia (APL), other subclasses of acute myeloid leukaemia and healthy donors, using high-throughput amplicon bisulfite sequencing wi...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-42543 | biostudies-arrayexpress
GenomicsGenome-wide study of DNA methylation in AML by MeDIP-seq
Methylated DNA immunoprecipitation followed by high-throughput sequencing (MeDIP-seq) has the potential to identify changes in DNA methylation important in cancer development. In order to understand the role of epigenetic modulation in the development of acute myeloid leukemia (AML) we have applied ...
ORGANISM(S): Homo sapiens 
2012-04-02 | E-GEOD-28314 | biostudies-arrayexpress
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