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MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
MetabolomicsDivergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies. The complex metabolic relationships that exist between members of the intestinal m...
2017-03-03 | MTBLS422 | MetaboLights
UnknownMicrotubule dynamics at the growth cone are mediated by α7 nicotinic receptor activation of a Gαq and IP3 receptor pathway.
Not available
S-EPMC4062821 | biostudies-literature
UnknownCD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.
Not available
S-EPMC524836 | biostudies-literature
UnknownPredictive evolutionary modelling for influenza virus by site-based dynamics of mutations.
Not available
S-EPMC10958014 | biostudies-literature
UnknownProteomic Profiling of the Large-Vessel Vasculitis Spectrum Identifying Shared Signatures of Innate Immune Activation and Stromal Remodeling.
Not available
S-EPMC12209745 | biostudies-literature
UnknownIntravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials.
Not available
S-EPMC10600726 | biostudies-literature
UnknownInflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution.
Not available
S-EPMC8477897 | biostudies-literature
UnknownModulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts.
Not available
S-EPMC7605524 | biostudies-literature
UnknownA "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis.
Not available
S-EPMC3655974 | biostudies-literature
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