Sort   by:  
 Page size 
TranscriptomicsMAZR and mast cells
Mast cells are known to be the key players in type I hypersensitivity reactions in humans and mice. They are critically involved in the development of allergic rhinitis, allergic asthma and systemic anaphylaxis. In this study we investigated the role of the transcriptional regulator MAZR in mast cel...
ORGANISM(S): Mus musculus 
2013-10-18 | E-MTAB-1816 | biostudies-arrayexpress
TranscriptomicsTwo functionally distinct subsets of mast cells generated through IL-2 independent CD25 activities
CD25 (IL-2R) can be expressed on the surface of immune cells in the absence of other chains of the interleukin-2 receptor (IL-2R), which are indispensable for IL-2 signaling. We identified two novel mast cell subsets, characterized by the differential expression of surface CD25, and by the ability t...
ORGANISM(S): Mus musculus 
2014-08-03 | E-GEOD-52502 | biostudies-arrayexpress
TranscriptomicsExpression data from HMC-1 mast cells
We demonstrate that the G protein Gi3 is the cellular target of the adenosine A3 receptor (A3R). By using a cell permeable peptide comprising the C-terminal end of Gαi3 fused to an importation sequence (ALL1) as a selective inhibitor of Gi3 signaling, we show that by coupling to Gi3, the A3R stimu...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-19888 | biostudies-arrayexpress
TranscriptomicsStem cell factor programs the mast cell activation phenotype
Mast cells, activated by antigen via the high affinity receptor for IgE (FcεRI), release an array of pro-inflammatory mediators that contribute to allergic disorders such as asthma and anaphylaxis. The KIT ligand, stem cell factor (SCF), is critical for mast cell expansion, differentiation and survi...
ORGANISM(S): Mus musculus 
2012-05-01 | E-GEOD-35332 | biostudies-arrayexpress
MetabolomicsMetabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
TranscriptomicsTranscription profiling of human lung and tonsillar mast cells
GeneChip Data of human lung mast cells and tonsillar mast cells
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1848 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of canine cutaneous mast cell tumor
In the present study, canine mast cell tumor (MCT) transcriptome was characterized in order to identify a set of candidate genes potentially useful for MCT classification and prognosis prediction. Fifty-one canine MCT biopsies were enrolled in the study. Isolated and purified total RNAs were individ...
ORGANISM(S): Canis lupus familiaris 
2014-05-06 | E-GEOD-50433 | biostudies-arrayexpress
TranscriptomicsMurine bone marrow-derived mast cells (BMMCs) transduced with pAPM lentiviruses overexpressing miR-221 vs control overexpressing miR-221m.
Bone marrow-derived mast cells were derived from three different female C57Bl/6 mice of similar age. Cells were transduced with pAPM lentiviruses either overexpressing microRNA-221 or a non functional microRNA-221 mutant, termed miR-221m, where four point-mutations were introduced in the seed sequen...
ORGANISM(S): Mus musculus 
2011-11-23 | E-GEOD-24462 | biostudies-arrayexpress
TranscriptomicsMast cells in response to some pathogens elicit a transcriptional program devoid of type I IFN response
Although mast cells elicit proinflammatory and type I IFN responses upon VSV infection, in response to L.monocytogenes (L.m) or S. Typhimurium (S.t), such cells elicit a transcriptional program devoid of type I IFN response. Balanced induction of proinflamatory and type I interferon (IFN) response...
ORGANISM(S): Mus musculus 
2009-12-31 | E-GEOD-18500 | biostudies-arrayexpress
ProteomicsSynovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis
Mast cells are phenotypically and functionally highly heterogeneous, and their state is possibly controlled by their local microenvironment. Therefore, concrete analyses are needed to understand whether mast cells act as powerful motivators or dispensable bystanders in specific diseases. Here, we ev...
ORGANISM(S): Homo sapiens (Human) 
2024-01-07 | PXD038584 | Pride
Ra • synovial microenvironment • mast cells • mrgprx2 
Sort   by:  
 Page size