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MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
TranscriptomicsAspergillus nidulans: Control (0 h starvation) vs. induction of starvation (12 h and 24 h) for WT, delta xprG and delta atmA
Transcriptional profiling of A. nidulans comparing starvation for 0 (reference), 12 and 24 h. The main objective was to identify genes specifically regulated during starvation by atmA and xprG. The results of the experiment were further validated by real-time PCR. Experimental procedure: Three A. ni...
ORGANISM(S): Emericella nidulans 
2012-12-07 | E-GEOD-42732 | biostudies-arrayexpress
GenomicsGlobal H-NS counter-silencing by LuxR activates quorum sensing gene expression
Global H-NS counter-silencing by LuxR activates quorum sensing gene expression
PRJNA561130 | ENA
TranscriptomicsTranscription profiling of fission yeast with deletion or overexpression of ste11 and changes in gene expression after nitrogen starvation of h plus, h minus, h90fus1 and h90ste11 cells to investigate control of gene expression during early sexual differentiation
Fission yeast cells belong to one of two specialized cell types, M or P. Specific environmental conditions trigger sexual differentiation, which leads to an internal program starting with pheromone signalling between M and P cells, followed by mating, meiosis and sporulation. The initial steps of ...
ORGANISM(S): Schizosaccharomyces pombe 
2006-09-22 | E-TABM-139 | biostudies-arrayexpress
GenomicsGlobal H-NS counter-silencing by LuxR activates quorum sensing gene expression [RNA-seq]
Global H-NS counter-silencing by LuxR activates quorum sensing gene expression [RNA-seq]
PRJNA561542 | ENA
GenomicsGlobal H-NS counter-silencing by LuxR activates quorum sensing gene expression
Bacteria coordinate cellular behaviors using a cell-cell communication system termed quorum sensing. In Vibrio harveyi, the master quorum sensing transcriptional factor LuxR directly regulates >100 genes in response to changes in population density. Here, we show that LuxR derepresses quorum sensing...
ORGANISM(S): Vibrio campbellii 
2019-11-01 | GSE136050 | GEO
TranscriptomicsGlobal H-NS counter-silencing by LuxR activates quorum sensing gene expression [RNA-seq]
Bacteria coordinate cellular behaviors using a cell-cell communication system termed quorum sensing. In Vibrio harveyi, the master quorum sensing transcriptional factor LuxR directly regulates >100 genes in response to changes in population density. Here, we show that LuxR derepresses quorum sensing...
ORGANISM(S): Vibrio campbellii 
2019-11-01 | GSE136191 | GEO
TranscriptomicsTranscription profiling of human lung adenocarcinoma A549 cells treated with vehicle (DMSO) or Etoposide (ETOP, 10 uM ), Benzo(a)pyrene Cryptolepineand 2-Amino-1-methyl-6-phenylimidazo [4,5-b]pyridine for 6 h, 16 h, 24 h, 48 h and 72 h
Title: Prediction of cell cycle behaviour in response to DNA damage agents via transcriptomic approach
Description: Human lung adenocarcinoma A549 cells were treated with vehicle (DMSO) or Etoposide (ETOP, 10 M-BM-5M ), Benzo(a)pyrene (BaP, 25 M-BM-5M ), Cryptolepine ( CLP, 2.5 M-BM-5M) and 2...
ORGANISM(S): Homo sapiens 
2006-06-01 | E-MIMR-102 | biostudies-arrayexpress
GenomicsHistone H2B ubiquitylation represses gametogenesis by opposing RSC-Dependent chromatin remodeling at the ste11 master regulator locus
Chromatin modifications play a pivotal role in cell fate decision. In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis when cells starve. The methylation of H3K4 by Set1-COMPASS and consequent promoter nucleosome deacetylation w...
ORGANISM(S): Schizosaccharomyces pombe 
2016-07-22 | E-GEOD-80524 | biostudies-arrayexpress
TranscriptomicsGm heat 30 min & 5 h
control plants vs heat treated plants (30 min & 5 h)
ORGANISM(S): Glycine max 
2015-08-12 | E-MTAB-2852 | biostudies-arrayexpress
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