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TranscriptomicsGene expression changes resulting from the stable loss of BAP1 in uveal melanoma cell lines
Uveal melanoma is a highly aggressive cancer with a strong propensity for metastasis, yet little is known about the biological mechanisms underlying this metastatic potential. We recently showed that most metastasizing uveal melanomas, which exhibit a class 2 gene expression profile, contain inactiv...
ORGANISM(S): Homo sapiens 
2013-09-06 | E-GEOD-48863 | biostudies-arrayexpress
TranscriptomicsGlobal expression analysis of BAP1 knockdown in transfected 92.1 cells
Analysis of the effect that reduced BAP1 levels have on global gene expression.The hypothesis tested was that reduction in BAP1 levels would produce changes in gene expression similar to changes observed in class 2 uveal melanomas. Data provided insight into genes that are disrupted with reduced BAP...
ORGANISM(S): Homo sapiens 
2011-01-06 | E-GEOD-24896 | biostudies-arrayexpress
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