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TranscriptomicsMaternal diabetes alters transcriptional programs in the developing embryo.
Exposure to maternal diabetes during pregnancy alters transcriptional profiles in the developing embryo. The enrichment, within the set of de-regulated genes, of those encoding transcriptional regulatory molecules provides support for the hypothesis that maternal diabetes affects specific developme...
ORGANISM(S): Mus musculus 
2012-09-25 | E-GEOD-41095 | biostudies-arrayexpress
MetabolomicsGut Microbiome and Serum Metabolic Alterations in Recurrent Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is a common complication of pregnancy, particularly affecting multiparous women with a history of GDM, who face a recurrence risk approaching 50%. This study investigates the association between gut microbiota modifications and metabolic profiles from early to ...

2025-07-21 | MTBLS12326 | MetaboLights
MetabolomicsBilophila wadsworthia inhibits lifestyle intervention response in Gestational Diabetes Mellitus via L-glutamine regulation

Fecal samples were collected from 26 pregnant women with gestational diabetes mellitus (GDM) prior to and following a lifestyle intervention study, and subsequently analyzed using untargeted metabolomics.

2026-04-16 | MTBLS13807 | MetaboLights
TranscriptomicsTranscription profiling of mouse embryos exposed to diabetes reveals maternal diabetes alters transcriptional programs in the developing embryo
Diabetic embryopathy can affect any developing organ system, although cardiovascular malformations, neural tube defects and caudal dysgenesis syndrome are the most prominent congenital malformations. We hypothesize that the metabolic imbalance occurring in diabetic pregnancy de-regulates tissue spec...
ORGANISM(S): Mus musculus 
2009-08-07 | E-GEOD-9675 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of maternal urine can aid clinical management of Gestational Diabetes Mellitus (GDM)
Not available
ORGANISM(S): Homo sapiens 
ST000398 | MetabolomicsWorkbench
TranscriptomicsGene expression profile in offspring born before vs. after maternal bariatric surgery
Evaluate differences in gene expression levels between offspring born after maternal bariatric surgery and their siblings born before surgery Offspring born after maternal bariatric surgery (AMS, N=23) vs. offspring born before maternal surgery (BMS, N=23)
ORGANISM(S): Homo sapiens 
2013-05-16 | E-GEOD-44407 | biostudies-arrayexpress
TranscriptomicsGene analysis of the neonatal rat lung exposed to STZ-induced maternal diabetes
Maternal diabetes is associated with a wide range of fetal and neonatal adverse effects including pulmonary disturbances. To investigate the effects of maternal diabetes on neonatal lung gene expression profile, we performed microarray analysis on the lungs of 14-day-old rats born to diabetic dam. ...
ORGANISM(S): Rattus norvegicus 
2009-01-07 | E-GEOD-14307 | biostudies-arrayexpress
TranscriptomicsMaternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice-the long term restoration
Early-life antibiotic exposure perturbs the intestinal microbiota, alters innate intestinal immunity, and accelerates type 1 diabetes development in the NOD mouse model. Here we found that maternal cecal microbiota transfer (CMT) to NOD mice with early-life antibiotic perturbation partially rescued ...
ORGANISM(S): Mus musculus 
2021-09-02 | E-MTAB-9982 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of microRNAs from peripheral blood mononuclear cells of gestational diabetes mellitus patients
The oligo micoarrays were used to determine gene expression profiles of peripheral blood mononuclear cells from gestational diabetes mellitus (GDM) patients.
ORGANISM(S): Homo sapiens 
2012-08-23 | E-MEXP-3382 | biostudies-arrayexpress
ProteomicsIdentification of the novel function of adipocyte plasma membrane associated protein (APMAP) in gestational diabetes mellitus by proteomic analysis of omental adipose tissues
Gestational diabetes mellitus (GDM) is considered as the early stage of type 2 diabetes mellitus. In this study, we compared the demographic and clinical data between six GDM and six NGT (healthy controls) and found the HOMA-IR was increased in GDM. Previously, many researches had proved that omenta...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080798 | MassIVE
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