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MetabolomicsNormalization techniques for PARAFAC modeling of urine metabolomics data
One of the body fluids often used in metabolomics studies is urine. The peak intensities of metabolites in urine are affected by the urine history of an individual resulting in dilution differences. This requires therefore normalization of the data to correct for such differences. Two normalization ...
2017-05-11 | MTBLS290 | MetaboLights
UnknownMathematical Modeling to Guide Experimental Design: T Cell Clustering as a Case Study.
Not available
S-EPMC9548402 | biostudies-literature
TranscriptomicsModeling Familial Cancer with iPSC Approaches
In vitro modeling of human disease has recently become feasible with the adoption of induced pluripotent stem cell (iPSC) technology. Here, we established patient-derived iPSCs from an Li-Fraumeni Syndrome (LFS) family and investigated the role of mutant p53 in the development of osteosarcoma (OS). ...
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-58123 | biostudies-arrayexpress
UnknownProspects for Declarative Mathematical Modeling of Complex Biological Systems.
Not available
S-EPMC6677696 | biostudies-literature
GenomicsCombining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer with CancerInSilico
Combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer with CancerInSilico
PRJNA471189 | ENA
ProteomicsElucidating drug mechanistics and resistance in HER2-positive breast cancer cell lines by mathematical modeling
Advancing precision medicine in the field of cancer is still curbed by the fact that a rational basis to predict treatment outcome is missing. To unravel the mechanism behind targeted drugs (trastuzumab, pertuzumab, erlotinib), mathematical modeling employing ordinary differential equations (ODE) wa...
ORGANISM(S): Homo sapiens 
2016-12-31 | GSE55891 | GEO
UnknownLeveraging public AI tools to explore systems biology resources in mathematical modeling.
Not available
S-EPMC11799200 | biostudies-literature
UnknownMathematical Models of Cancer: When to Predict Novel Therapies, and When Not to.
Not available
S-EPMC6764933 | biostudies-literature
TranscriptomicsMathematical modeling of Trypanosoma brucei transcription
Trypanosome RNA polymerase II transcription is polycistronic, individual mRNAs being excised by trans splicing and polyadenylation. In this study, we refined the previously published mathematical model for bloodstream form parasites and extended it to the procyclic form. We used the model, together ...
ORGANISM(S): Trypanosoma brucei 
2016-03-16 | E-GEOD-79208 | biostudies-arrayexpress
UnknownMathematical modeling of laser lipolysis.
Not available
S-EPMC2292728 | biostudies-literature
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