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Viruses manipulate host cells to enhance their replication, and the identification of host factors targeted by viruses has led to key insights in both viral pathogenesis and cellular physiology. We previously described global changes in cellular protein levels during human immunodeficiency virus (HI...
ORGANISM(S): Homo sapiens (Human) 
2019-03-08 | PXD012263 | Pride
The seminal description of cellular restriction factor APOBEC3G and its antagonism by HIV-1 Vif has underpinned two decades of research on the host-virus interaction. As well as APOBEC3G and its homologues, however, we have recently discovered that Vif is also able to degrade the PPP2R5 family of re...
ORGANISM(S): Homo sapiens (Human) 
2020-04-17 | PXD018271 | Pride
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