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TranscriptomicsGene expression changes in the cerebellum, cortex and spinal cord of MATR3 S85C knock-in mice at pre-symptomatic stage 8-10 weeks of age
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by motor neuron degeneration. MATR3 is an ALS-linked gene that encodes an RNA-binding protein that is involved in alternative splicing regulation. S85C is the most commonly identified mutation in MATR3. We ...
ORGANISM(S): Mus musculus 
2020-08-18 | E-MTAB-8838 | biostudies-arrayexpress
ProteomicsDDX1 Methylation Mediated MATR3 Splicing Regulates Intervertebral Disc Degeneration by Initiating Chromatin Reprogramming
Low back pain (LBP), often caused by intervertebral disc degeneration (IVDD), poses a major challenge in aging populations. DDX1, an RNA-binding protein, plays key roles in RNA metabolism but its function in IVDD remains unclear. We identify DDX1 as a non-histone substrate of lysine methyltransferas...
ORGANISM(S): Homo Sapiens 
2025-05-29 | PXD064432 |
GenomicsMATR3
MATR3
PRJNA823719 | ENA
GenomicsMATR3-binding RNAs in ES cells [RIP-Seq]
MATR3-binding RNAs in ES cells [RIP-Seq]
PRJNA935806 | ENA
GenomicsMATR3-binding RNAs in AML12 cells [RIP-Seq]
MATR3-binding RNAs in AML12 cells [RIP-Seq]
PRJNA823726 | ENA
TranscriptomicsiCLIP of MATR3 from C57BL/6J wildtype mice
The aim of the experiment was to find binding sites MATR3 in mouse brain tissue. Whole brain was prepped from mice at P0 and replicates are from separate animals.
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-6283 | biostudies-arrayexpress
GenomicsMATR3 II
MATR3 II
PRJNA935803 | ENA
GenomicsMATR3 pathogenic variants differentially impair its cryptic splicing repression function
MATR3 pathogenic variants differentially impair its cryptic splicing repression function
PRJNA844547 | ENA
GenomicsiCLIP of MATR3 from C57BL/6J wildtype mice
iCLIP of MATR3 from C57BL/6J wildtype mice
PRJEB23795 | ENA
GenomicsMATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy
MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy
PRJNA863308 | ENA
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