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TranscriptomicsComparison of Hepatocyte nuclear factor 4 alpha developmental and temporal knockout mice
The goal of this experiment was to distinguish those genes regulated following acute HNF4alpha depletion compared to a developmental knockout model where gene compensation may comfound results. Expression profile of livers from 8 week old male Hnf4alpha Flox mice that express either albumin cre or t...
ORGANISM(S): Mus musculus 
2012-02-21 | E-GEOD-34581 | biostudies-arrayexpress
TranscriptomicsIdentification of baseline gene expression signatures predicting therapeutic responses to three biologic agents in rheumatoid arthritis: a retrospective observational study
The aim of this study was to identify the specific molecular biological features predicting the therapeutic outcomes of three bDMARDs, infliximab (IFX), tocilizumab (TCZ), and abatacept (ABT) by studying blood gene expression signature of patients prior to biologic treatment in a unified test platfo...
ORGANISM(S): Homo sapiens 
2016-07-21 | E-GEOD-78068 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of side population cells of mouse thyroid before and after partial thyroidectomy
Side population (SP) cells are enriched with genes involved in stem cell activity and/or lineage specifications. Stem cell marker genes are upregulated after partial thyroidectomy. Four-condition experiment: control side population (CSP) vs. control main population (CMP) vs. thyroidectomized side po...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-34513 | biostudies-arrayexpress
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