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UnknownTreatment following Triple-AAV Delivery in Mature Murine Model of Human CDH23-Associated Hearing Loss.
Not available
S-EPMC10741579 | biostudies-literature
TranscriptomicsTranscription profiling of mouse strains A/J versus C57BL/6J during diet-induced obesity
The effects of high-fat (HF) feeding on the gene expression in the small intestine were examined using obesity-resistant A/J mice and obesity-sensitive C57BL/6J (B6) mice. Both strains of mice were maintained on low-fat (LF, 5% fat) or HF (30% fat) diets for two weeks. Oligonucleotide microarray and...
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-3433 | biostudies-arrayexpress
UnknownRisperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1.
Not available
S-EPMC8289890 | biostudies-literature
GenomicsNext Generation Mendelian Genetics: Kabuki Syndrome

The ultimate purpose of this research is to identify genes causing hereditary disorders. We are scaling a new approach to identify the candidate genes and gene mutations that underlie rare human Mendelian (a set of primary tenets relating to the transmission of hereditary characteristics from...

phs000295.v1.p1 | EGA
TranscriptomicsExpression data from synovium, bone marrow and nucleus pulposus
Synovial and bone marrow mesenchymal stem cells after intradiscally injection show regenerative effects of nucleus pulposus. Microarray analyses of rats were performed to investigate the closeness of the gene profiles between the nucleus pulposus cells and the synovial or bone marrow mesenchymal ste...
ORGANISM(S): Rattus norvegicus 
2010-10-11 | E-GEOD-24612 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse kidney from Aquaporin-11 knockout effect
Aquaporin-11 (AQP11), a new member of the aquaporin family, is localized in the endoplasmic reticulum (ER). Aqp11–/– mice neonatally suffer from polycystic kidneys derived from the proximal tubule. Its onset is proceeded by the vacuolization of ER. However, the mechanism for the formation of ...
ORGANISM(S): Mus musculus 
2008-10-26 | E-GEOD-10634 | biostudies-arrayexpress
TranscriptomicsHuman transcripts up-regulated in the human mesenchymal stem cells migrated within the synovium
After the injection of human synovial mesenchymal stem cells into the rat (Lewis strain) knee joint, synovium was investigated using species specific microarray analyses of human and rat transcripts to investigate the gene expression change after injection. Human synovial mesenchymal stem cells were...
ORGANISM(S): Homo sapiens 
2014-09-22 | E-GEOD-61617 | biostudies-arrayexpress
UnknownLipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKϵ-IRF3 axis activation.
Not available
S-EPMC6028956 | biostudies-literature
TranscriptomicsTranscription profiling of mouse liver from animals exposed to social stress
Social stress is well known to be involved in the occurrence and exacerbation of mental illness, and also various life-style related diseases such as hyperinsulinemia, hyperglycemia, cardiovascular diseases and cancer. However, there is little information on tissue-specific gene expression in respon...
ORGANISM(S): Mus musculus 
2009-04-19 | E-GEOD-12693 | biostudies-arrayexpress
UnknownA missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association.
Not available
S-EPMC10275923 | biostudies-literature
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