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Huntington's disease (HD) is a dominantly inherited genetic disease caused by mutant huntingtin (htt) protein with expanded polyglutamine tracts. A neuropathological hallmark of HD is the presence of neuronal inclusions of mutant htt. p62 is an important regulatory protein in selective autophagy, ...
ORGANISM(S): Mus musculus 
Ten-week-old male mice (WT and ob/ob) were starved for 0, 2, 4, 6, 8, 12, 16, and 24 hours and liver samples were collected. Total proteins extracted during sample preparation of metabolomic analysis were subjected to the following phosphoproteomic analysis. As described above, 2 mg of protein solut...
ORGANISM(S): Mus Musculus (mouse) 
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