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UnknownAssociations of LRP5 and MTHFR Gene Variants with Osteoarthritis Prevalence in Elderly Women: A Japanese Cohort Survey Randomly Sampled from a Basic Resident Registry.

Objective

Osteoarthritis (OA) is a common and degenerative joint disorder in the elderly. A greater importance of understanding the relationship between genetic factors and OA prevalence has emerged with population aging. We therefore investigated the associations of several bone disease-rel...
S-EPMC8488030 | biostudies-literature
UnknownIL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4<sup>+</sup> T cells.
Malaria infection elicits both protective and pathogenic immune responses, and IL-27 is a critical cytokine that regulate effector responses during infection. Here, we identified a critical window of CD4+ T cell responses that is targeted by IL-27. Neutralization of IL-27 during acute inf...
S-EPMC10701605 | biostudies-literature
UnknownOxygen isotopes of anhydrous primary minerals show kinship between asteroid Ryugu and comet 81P/Wild2.
The extraterrestrial materials returned from asteroid (162173) Ryugu consist predominantly of low-temperature aqueously formed secondary minerals and are chemically and mineralogically similar to CI (Ivuna-type) carbonaceous chondrites. Here, we show that high-temperature anhydrous primary minerals ...
S-EPMC9757743 | biostudies-literature
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