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TranscriptomicsDNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas
Elevated DNA methylation in the first intronic region of the BCL6 locus in B cell lymphomas enforces transcription of the BCL6 gene Promoter tiling arrays were used to investigate the distribution of DNA methylation near the promoter region of BCL6 locus Comparison of DNA methylation at promoter reg...
ORGANISM(S): Homo sapiens 
2010-08-20 | E-GEOD-22884 | biostudies-arrayexpress
TranscriptomicsDamID for MBD3 in human breast cancer cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-44776 | biostudies-arrayexpress
TranscriptomicsThe transcription factors Snail and Slug activate the TGF-B signaling pathway in breast cancer
Gene expression profiling to determine transcriptome changes following Snail or Slug expression in MCF-7 breast cancer cells Samples were isolated in three biological replicates for microarray analysis. Four MCF-7 breast cancer cell subsets: MCF-7(untreated), MCF-7 (with Control adenovirus), MCF-7 ...
ORGANISM(S): Homo sapiens 
2011-10-20 | E-GEOD-29672 | biostudies-arrayexpress
TranscriptomicsDamID for MBD3 in human breast cancer cell lines [Tiling Arrays]
Maintenance of chromatin structure is essential to eukaryotic life; dysregulation is known to be causal for aberrant development and disease. The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin structure by nucleosome remodel...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-44774 | biostudies-arrayexpress
TranscriptomicsDamID for MBD3 in human breast cancer cell lines [Promoter_Arrays]
Maintenance of chromatin structure is essential to eukaryotic life; dysregulation is known to be causal for aberrant development and disease. The Mi-2/nucleosome remodeling and histone deacetylase (NuRD) complex is a multiprotein machine proposed to regulate chromatin structure by nucleosome remodel...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-GEOD-44773 | biostudies-arrayexpress
TranscriptomicsAnalysis of gene expression during glucocorticoid-induced apoptosis of rat primary thymocytes
Glucocorticoids induce rapid apoptosis of rat primary thymocytes through mechanisms requiring altered gene expression. The determination of genes regulating glucocorticoid-induced apoptosis of lymphocytes has received considerable attention. However, the role of specific non-coding microRNAs in the ...
ORGANISM(S): Rattus norvegicus 
2014-03-26 | E-GEOD-45560 | biostudies-arrayexpress
TranscriptomicsRunx2 Transcriptome of Prostate Cancer Cells: Insights into Invasiveness and Bone Metastasis
Background: Prostate cancer (PCa) cells preferentially metastasize to bone at least in part by acquiring osteomimetic properties. Runx2, an osteoblast master transcription factor, is aberrantly expressed in PCa cells, and promotes their metastatic phenotype. The transcriptional programs regulated by...
ORGANISM(S): Homo sapiens 
2010-12-26 | E-GEOD-24261 | biostudies-arrayexpress
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