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TranscriptomicsAnti-CD27 immunotherapy induces intratumoral immunostimulation in B-cell lymphoma: the multicenter RiVa trial (RNA-Seq Data for RiVa)
The clinical utility of T-cell agonistic antibodies in cancer therapy, much less their ability to stimulate intratumoral T-cells in patients, has eluded us. T-cell agonistic antibodies such as anti-CD27 can induce clinically meaningful anti-tumor activity. The combination of anti-CD27 agonist varlil...
ORGANISM(S): Homo sapiens 
2025-08-09 | E-MTAB-14594 | biostudies-arrayexpress
TranscriptomicsGenome-wide distribution of the three condensin complexes in C. elegans
Condensins are multi-subunit protein complexes that regulate chromosome structure throughout cell-cycle. Metazoans contain two types of condensin complexes (I and II) with essential and distinct functions. In C. elegans a third type of condensin (IDC) functions as part of the X chromosome dosage com...
ORGANISM(S): Caenorhabditis elegans 
2013-09-16 | E-GEOD-45678 | biostudies-arrayexpress
ProteomicsMolecular analysis of clinically defined subsets of high-grade serous ovarian cancer
The diversity and heterogeneity within high-grade serous ovarian cancer (HGSC) is not well understood. Comprehensive molecular analyses were performed including high-pass whole-genome sequencing, targeted deep DNA sequencing, RNA sequencing, reverse-phase protein arrays, mass spectrometry-based prot...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD014980 | Pride
Human Ovarian cancer Tissue 
UnknownMolecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.
Not available
S-EPMC7234854 | biostudies-literature
UnknownTGFB2 mutations cause familial thoracic aortic aneurysms and dissections associated with mild systemic features of Marfan syndrome.
Not available
S-EPMC4033668 | biostudies-literature
UnknownAnastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial.
Not available
S-EPMC4769326 | biostudies-literature
UnknownQuantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset.
Not available
S-EPMC3959810 | biostudies-literature
UnknownJoint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia.
Not available
S-EPMC3852929 | biostudies-literature
UnknownCommon and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.
Not available
S-EPMC3724194 | biostudies-literature
UnknownPathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Not available
S-EPMC4129409 | biostudies-literature
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