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MetabolomicsMetabolomic Profiling of Renal Cyst Fluid in Advanced ADPKD: Insights from Dialysis and Transplantation Cohorts

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by progressive renal cyst formation, often leading to end-stage kidney disease (ESKD). While urinary metabolomics in ADPKD has been extensively studied, the composition of renal cyst fluid, par...

2025-07-07 | MTBLS12372 | MetaboLights
UnknownFRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments.
Not available
S-EPMC7364478 | biostudies-literature
ProteomicsDynamic regulation of the proteome and lysine acetylome of Chlamydomonas reinhardtii in dependence on light and acetate
Here, we performed a mass spectrometry-based analysis to study lysine acetylation and proteome dynamics in Chlamydomonas under varying growth conditions. Liquid cultures of Chlamydomonas were transferred from mixotrophic (light and acetate as carbon source) to heterotrophic (dark and acetate), or ph...
ORGANISM(S): Chlamydomonas Reinhardtii 
2021-11-19 | PXD025168 | JPOST Repository
UnknownLessons learned from a pilot implementation of physical activity recommendations in axial spondyloarthritis exercise group therapy.
Not available
S-EPMC8762948 | biostudies-literature
ProteomicsMicrobial functionality as affected by experimental warming of a temperate mountain forest soil - a metaproteomics survey
Soils are a huge reservoir of organic C, and the efflux of CO2 from soils is one of the largest fluxes in the global C cycle. Out of all natural environments, soils probably contain the greatest microbial biomass and diversity, which classifies them as one of the most challenging habitats for microb...
ORGANISM(S): uncultured soil microorganism 
2022-03-14 | PXD004428 | Pride
Soil microbial diversity Microbial community functionality Soil warming 
UnknownThe complete sequence of the mitochondrial genome of Nautilus macromphalus (Mollusca: Cephalopoda).
Not available
S-EPMC1544340 | biostudies-literature
MetabolomicsShotgun lipidomics of HeLa whole-cell lysates and lysosomes following LLOMe treatment

Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach, we here identified the bridge-like lipid transport protein VPS13C/PARK23 as a key component of a...

2026-07-03 | MTBLS14737 | MetaboLights
no omics definedTranscription profiling of human Vg9/Vd2 T cells after 72h stimulation with HMB-PP in the presence of IL-2, IL-4, or IL-21
Hver2.1.1 microarrays containing ~15,000 genes were used to characterize the gene expression profiles of Vg9/Vd2 T cells upon 72h stimulation with HMB-PP in the presence of IL-2, IL-4, or IL-21.
ORGANISM(S): Homo sapiens 
2007-03-21 | E-MEXP-763 | biostudies-arrayexpress
UnknownEstrogen-mediated downregulation of HIF-1α signaling in B lymphocytes influences postmenopausal bone loss.
Not available
S-EPMC8854586 | biostudies-literature
ProteomicsDecoding the complete arsenal for cellulose and hemicellulose deconstruction in the highly efficient cellulose decomposer Paenibacillus O199
The search for new enzymes and microbial strains to degrade plant biomass is one of the most important strategies for improving the conversion processes in the production of environment-friendly chemicals and biofuels. In this study, we report a new Paenibacillus isolate, O199, which showed the high...
ORGANISM(S): Paenibacillus sp. 
2016-04-26 | PXD003970 | Pride
Proteomics Gelc-ms/ms Cellulose degradation 
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