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ProteomicsPrP concentration in the central nervous system: regional variability, genotypic effects, and pharmacodynamic impact
Prion protein (PrP) concentration controls the kinetics of prion replication and is a genetically and pharmacologically validated therapeutic target for prion disease. In order to evaluate PrP concentration as a pharmacodynamic biomarker and assess its contribution to known prion disease risk factor...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2022-02-28 | PXD031432 | panorama
TranscriptomicsGenomic Analysis of wig-1 Pathways
Analysis of wig-1 pathways via suppression of Wig-1 by antisense oligonucleotides Total RNA obtained from mouse brain subjected to antisense oligonucleotide (ASO) treatement compared to PBS (control), and negative control ASO brain treatment.
ORGANISM(S): Mus musculus 
2011-06-06 | E-GEOD-29751 | biostudies-arrayexpress
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