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UnknownPhase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes.
Not available
S-EPMC6136660 | biostudies-literature
TranscriptomicsThirteen-week Nose-only Inhalation Exposures of Propylene Glycol Aerosols in Sprague Dawley Rats with a Lung Systems Toxicology Analysis.
Propylene glycol (PG) is a common carrier in e-vapor formulations and its properties have been extensively studied. In this 13-week subchronic nose-only inhalation study, Sprague Dawley rats were exposed to filtered air (sham control group), propylene glycol/water (PG/W; 90:10) or a propylene glycol...
ORGANISM(S): Rattus norvegicus 
2021-09-07 | E-MTAB-10006 | biostudies-arrayexpress
TranscriptomicsA 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysema following smoking cessation or switching to e-vapor products.
Cigarette smoking causes serious diseases, including lung cancer, heart disease, and emphysema. While cessation remains the most effective approach to minimize smoking-related disease, alternative non-combustible tobacco-derived nicotine containing products may reduce disease risks among those unabl...
ORGANISM(S): Mus musculus 
2021-03-18 | E-MTAB-9597 | biostudies-arrayexpress
UnknownA missense variant in SLC39A8 is associated with severe idiopathic scoliosis.
Not available
S-EPMC6177404 | biostudies-literature
UnknownThe epidemiological benefit of pyrethroid-pyrrole insecticide treated nets against malaria: an individual-based malaria transmission dynamics modelling study.
Not available
S-EPMC11584316 | biostudies-literature
UnknownExpert range maps of global mammal distributions harmonised to three taxonomic authorities.
Not available
S-EPMC9060555 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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