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TranscriptomicsTranscription profiling of bone marrow hematopoietic stem cells and myeloid progenitors from mice with conditional deletion of Forkhead O (FoxO) family of transcription factors
To investigate the role of FoxO transcription factors as mediators of hematopoietic stem cell resistance to oxidative stress. Experiment Overall Design: Study the effect of the deficiency of FoxO1, FoxO3, and FoxO4 in murine bone marrow hematopoietic stem cells and myeloid progenitors on expression ...
ORGANISM(S): Mus musculus 
2007-11-15 | E-GEOD-6623 | biostudies-arrayexpress
GenomicsDirect GR binding sites potentiate clusters of TF binding across the human genome [8]
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-79431 | biostudies-arrayexpress
GenomicsDirect GR binding sites potentiate clusters of TF binding across the human genome [6]
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-79429 | biostudies-arrayexpress
TranscriptomicsDirect GR binding sites potentiate clusters of TF binding across the human genome [3]
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-79426 | biostudies-arrayexpress
TranscriptomicsDirect GR binding sites potentiate clusters of TF binding across the human genome [2]
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-79425 | biostudies-arrayexpress
GenomicsDirect GR binding sites potentiate clusters of TF binding across the human genome
The glucocorticoid receptor (GR) binds the human genome at >10,000 sites, but only regulates the expression of hundreds of genes. To determine the functional effect of each site, we measured the glucocorticoid (GC) responsive activity of nearly all GR binding sites (GBSs) captured using chromatin im...
ORGANISM(S): Homo sapiens 
2016-08-25 | E-GEOD-77869 | biostudies-arrayexpress
TranscriptomicsRetinoids induce rapid dynamic changes in the non-coding RNAs and epigenetic profiles of murine Hox clusters (ChIP-chip)
Physiologically relevant concentrations of retinoic acid are added to Mouse ES cells and a time course (0-72 hours) is examined with tiling array ChIP-chip and RNA-seq to characterize the early dynamics of expression of coding and non-coding RNAs and epigenetics in and around the Hox clusters. Expre...
ORGANISM(S): Mus musculus 
2015-04-27 | E-GEOD-61584 | biostudies-arrayexpress
TranscriptomicsRetinoids induce rapid dynamic changes in the non-coding RNAs and epigenetic profiles of murine Hox clusters (tiling)
Physiologically relevant concentrations of retinoic acid are added to Mouse ES cells and a time course (0-72 hours) is examined with expression tiling arrays to characterize the early dynamics of expression of coding and non-coding RNAs in and around the Hox clusters. Gene expression is examined at ...
ORGANISM(S): Mus musculus 
2015-04-27 | E-GEOD-61585 | biostudies-arrayexpress
TranscriptomicsRetinoids induce rapid dynamic changes in the non-coding RNAs and epigenetic profiles of murine Hox clusters.
Physiologically relevant concentrations of retinoic acid are added to Mouse ES cells and a time course (0-72 hours) is examined with expression tiling arrays and RNA-seq to characterize the early dynamics of expression of coding and non-coding RNAs in and around the Hox clusters. Gene expression is ...
ORGANISM(S): Mus musculus 
2015-04-27 | E-GEOD-67610 | biostudies-arrayexpress
UnknownPrognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.
Not available
S-EPMC6254006 | biostudies-literature
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