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TranscriptomicsDual leucine zipper kinase is required for excitotoxicity induced neuronal degeneration
To investigate the role of DLK in the adult brain, we generated mice in which excision of the DLK allele can be temporally controlled to avoid the lethality observed at early postnatal ages in DLK null mice (Hirai et al., 2006). This was done by crossing mice with DLK exons 2-5 flanked by loxP sites...
ORGANISM(S): Mus musculus 
2013-08-28 | E-GEOD-50245 | biostudies-arrayexpress
TranscriptomicsWhole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (Affymetrix exon-level)
RNA derived from the L5 DRG 7 days following L5-SNT and from naïve L5-DRG tissue was subjected to microarray analysis and expression was determined at the exon and gene level 6 biological replicates (3 case – SNT subjected L5-DRG tissue, 3 control – naïve L5-DRG tissue). Each sample was made from po...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-53860 | biostudies-arrayexpress
TranscriptomicsWhole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (Affymetrix transcript-level)
RNA derived from the L5 DRG 7 days following L5-SNT and from naïve L5-DRG tissue was subjected to microarray analysis and expression was determined at the exon and gene level 6 biological replicates (3 case – SNT subjected L5-DRG tissue, 3 control – naïve L5-DRG tissue). Each sample was made from po...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-53764 | biostudies-arrayexpress
TranscriptomicsWhole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat, at different sequencing depths (RNA-Seq)
Poly(A) enriched RNA derived from the L5 DRG 7 days following L5-SNT and from naïve L5-DRG tissue was subjected to RNA-seq analysis at different sequencing depths 6 biological replicates (3 case – SNT subjected L5-DRG tissue, 3 control – naïve L5-DRG tissue). Each biological replicate was divided B4...
ORGANISM(S): Rattus norvegicus 
2014-01-07 | E-GEOD-53762 | biostudies-arrayexpress
TranscriptomicsGenome-wide Transcriptional Profiling of Skin and Dorsal Root Ganglia after Ultraviolet-B-Induced Inflammation
Ultraviolet-B (UVB) irradiation of the skin was performed on rat (skin and DRG) and human (skin) tissue. The resulting changes in gene expression were then profiled by using RNA-seq to compare gene expression between irradiated and non-irradiated samples Poly(A) selected RNA was sequenced for 5 irra...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-54413 | biostudies-arrayexpress
UnknownEffect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial.
Not available
S-EPMC8441591 | biostudies-literature
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