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TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MouseSca1 dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25636 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [Spleen dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Mus musculus 
2012-07-09 | E-GEOD-25637 | biostudies-arrayexpress
TranscriptomicsA mouse model of deregulation of the malt1 oncogene recapitulates the pathogenesis of human malt lymphoma [MALT dataset]
Attempts at modeling chromosomal translocations involving MALT1 gene, hallmarks of human mucosa-associated lymphoid tissue (MALT) lymphoma, have failed to reproduce the disease in mice. Here we describe a transgenic model in which MALT1 expression was targeted to mouse hematopoietic stem/progenitor ...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-25638 | biostudies-arrayexpress
TranscriptomicsAn integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma (Affymetrix HG-U133plus2 gene expression microarray)
Splenic marginal zone lymphoma (SMZL) is an indolent B-cell lymphoproliferative disorder characterised by 7q32 deletion, but the target genes of this deletion remain unknown. In order to elucidate the genetic target of this deletion, we performed an integrative analysis of the genetic, epigenetic, t...
ORGANISM(S): Homo sapiens 
2012-08-30 | E-GEOD-35426 | biostudies-arrayexpress
TranscriptomicsAn integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma (Main Study)
This SuperSeries is composed of the following subset Series: GSE35424: methylation analysis was carried out on 12 SMZL, 6 MCL and 6 FL cases by the Cambridge group using Illumina Infinium Human Methylation 27 Array GSE35425: Oligo aCGH on 21 SMZL cases were carried out by the Cambridge group using...
ORGANISM(S): Homo sapiens 
2012-08-30 | E-GEOD-21554 | biostudies-arrayexpress
UnknownPlasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer: the STAMPEDE Phase 3 Randomized Clinical Trial.
Not available
S-EPMC11869088 | biostudies-literature
UnknownMetformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol.
Not available
S-EPMC12303861 | biostudies-literature
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