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ProteomicsMCM9 is Required for Mammalian DNA Mismatch Repair
DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects innate DNA polymerase infidelities during replication to maintain genomic integrity. Defects in a subset of MMR genes are associated with hereditary non-polyposis colon cancer and some other sporadic cancers, highlighting...
ORGANISM(S): Homo sapiens (Human) 
2015-08-19 | PXD000212 | Pride
Mcm9 human dna replication helicase mmr mismatch repair 
UnknownProteomic data on the nuclear interactome of human MCM9.
Not available
S-EPMC4712314 | biostudies-literature
UnknownMolecular functions of MCM8 and MCM9 and their associated pathologies.
Not available
S-EPMC10291252 | biostudies-literature
UnknownMCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency.
Not available
S-EPMC5413161 | biostudies-literature
UnknownClinical syndromes linked to biallelic germline variants in MCM8 and MCM9.
Not available
S-EPMC12361757 | biostudies-literature
UnknownMCM9 mutations are associated with ovarian failure, short stature, and chromosomal instability.
Not available
S-EPMC4259971 | biostudies-literature
UnknownMCM9 is associated with germline predisposition to early-onset cancer-clinical evidence.
Not available
S-EPMC8460657 | biostudies-literature
UnknownMCM9 deficiency impairs DNA damage repair during spermatogenesis, leading to Sertoli cell-only syndrome in humans.
Not available
S-EPMC12218035 | biostudies-literature
UnknownControl of homologous recombination by the HROB-MCM8-MCM9 pathway.
Not available
S-EPMC6771392 | biostudies-literature
UnknownMotifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment.
Not available
S-EPMC7949153 | biostudies-literature
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