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MetabolomicsMDA-MB-231 cells and p38 gamma knockdown
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ORGANISM(S): Homo sapiens 
ST000043 | MetabolomicsWorkbench
MetabolomicsNormalization strategies for lipidome data in cell line panels & Distinct lipidomic profiles in breast cancer cell lines relate to proliferation and EMT phenotypes

Sample collection can significantly affect measurements of relative lipid concentrations in cell line panels, hiding intrinsic biological properties of interest between cell lines. Most quality control steps in lipidomic data analysis focus on controlling technical variation. Correcting for the t...

2025-08-07 | MTBLS9493 | MetaboLights
TranscriptomicsGene expression analysis in CITED2 knockdown MDA-MB-231 human breast cancer cells.
The goal of this experiment is to explore the mechanism behind CITED2 (a non-DNA binding transcriptional co-activator) metastatic action by comparing gene expression changes between shScramble and shCITED2-expressing MDA-MB-231 cells.
ORGANISM(S): Homo sapiens 
2017-01-14 | E-MTAB-4267 | biostudies-arrayexpress
ProteomicsProteomic characterization of MDA-MB-231 and MCF-10A breast cells exposed to 1 mT 50 Hz ELF for 4 hours
MDA-MB-231 breast cancer cells and MCF-10A breast cells were exposed to 1 mT 50 Hz extremely low-frequency magnetic field (ELF-MF) for 4 hours
ORGANISM(S): Homo Sapiens (human) 
2023-02-17 | PXD040120 | JPOST Repository
MetabolomicsDynamic single-cell metabolomics reveals cell-cell interaction between tumor cells and macrophages

Single-cell metabolomics reveals cell heterogeneity and elucidates intracellular molecular mechanisms. However, general concentration measurement of metabolites can only provide a static delineation of metabolomics, lacking the metabolic activity information of biological pathways. Herein, we dev...

2025-04-14 | MTBLS11091 | MetaboLights
TranscriptomicsExpression data of control-shRNA and SATB1-shRNA expressing MDA-MB-231 cells from 2D and 3D culture system
We examined whether SATB1 functions as a global gene regulator in order to maintain the aggressive phenotype of the MDA-MB-231 cell line. We compared the gene expression profiles between control_shRNA-MDA-MB-231 cells, which express SATB1 at high levels, and SATB1_shRNA1-MDA-MB-231 in which the leve...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-5417 | biostudies-arrayexpress
TranscriptomicsExpression profiling, MDA-MB-231-luc2 response to GW501516
MDA-MB-231-luc2 cells were treated with the PPARd specific agonist GW501516 and the resulting expression changes profiled.
ORGANISM(S): Homo_sapiens 
2013-06-25 | E-MTAB-1262 | biostudies-arrayexpress
Metabolomics1H-NMR metabolomics identifies hypoxanthine as a novel metastasis-associated metabolite
Breast cancer is one of the leading causes of death in females, mainly because of metastasis. Oncometabolites, produced via metabolic reprogramming, can influence metastatic signaling cascades. Accordingly, and based on our previous results, we hypothesized that metabolites from highly metastatic br...
2025-09-19 | MTBLS7764 | MetaboLights
TranscriptomicsMicroarray of CFH Knockdown in Breast Cancer Cell Line MDA-MB-231
Human breast cancer cell line MDA-MB-231 was transduced with lentivirus vector expressing non-specific control (NS) and CFH knockdown (shCFH1) sequences.
ORGANISM(S): Homo sapiens 
2023-09-05 | E-MTAB-13327 | biostudies-arrayexpress
MetabolomicsThe Poly (ADP-Ribose) Polymerase inhibitor Veliparib and Radiation Cause Significant Cell Line Dependent Metabolic Changes in Breast Cancer Cells
Breast tumors are characterized into different subtypes based on their surface marker expression, which affects their prognosis and treatment. For example, triple negative breast cancer cells (ER-/PR-/Her2-) show reduced susceptibility towards radiotherapy and chemotherapeutic agents. Poly (ADP-ribo...
2016-11-07 | MTBLS337 | MetaboLights
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