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ORGANISM(S): Homo sapiens 
To determine the absolute copy number of proteins in MDA-MB231 breast cancer cells, we employed IBAQ mediated absolute quantification of proteins based on (Schwanhäusser et al., Nature, 2011), with some modifications. Maqquant calculated iBAQ values were calibrated using spike-in standards, and used...
ORGANISM(S): Homo sapiens (Human) 
2021-05-14 | PXD024139 | Pride
By survival analysis of breast cancer patients, JMJD6 was found to be significantly associated with poor prognosis. Over-expression and knock-down of JMJD6 in breast cancer cell lines suggested a role in proliferation. In order to study the transcriptional events that occur following JMJD6 expressio...
ORGANISM(S): Homo sapiens 
We analysed the impact of LARP6 depletion on the proteome of actively growing MDA-MB231 breast cancer cells by SILAC. For this purpose, Light (L) SILAC-labelled MDA-MB231 cells were treated with non-targeting control (NT) or two independent LARP6 siRNA (18i & 97i) for 72 hrs, before lysis in 4% SDS,...
ORGANISM(S): Homo sapiens (Human) 
2020-10-20 | PXD021204 | Pride
Expression data from knockdown of UGT8 in MDA-MB231 cells
Mfng, a modulator of Notch signaling, is highly expressed in human claudin-low breast cancer (CLBC). To determine Mfng’s roles in CLBC pathogenesis,we knocked down Mfng in a CLBC cell line MDA-MB231, and found that Mfng knockdown altered Notch activation, decreased tumor sphere formation in vitro, a...
ORGANISM(S): Homo sapiens 
Analysis of expression changes of cultured HepG2 hepatoma, U87 glioma, and MDA-MB231 breast cancer cells subjected to hypoxia (0.5% O2) for 0, 4, 8, 12 hours . Results provide insight to cell type-specific response to hypoxia. HepG2 hepatoma, U87 glioma, and MDA-MB231 breast cancer cells were collec...
ORGANISM(S): Homo sapiens 
Gene expression profile of Serially Mixed samples of MDA-MB231 and Mouse Astrocytes
Transcriptomics analysis of NOP16-regulated genes in MDA-MB231 cells [RNA-seq]
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