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ProteomicsProteomic Analysis of Measles Virus Protein C-Host Interactions in an Infectious Context Using Recombinant Viruses
Viruses manipulate central machineries of host cells to their advantage. They prevent host cell antiviral responses in order to create a favourable environment for their survival and propagation. Measles virus (MV) encodes two non-structural proteins MV-V and MV-C, proposed to counteract the host in...
ORGANISM(S): Viruses Homo sapiens (Human) 
2021-01-19 | PXD015316 | Pride
Human Infection Interactomic Measle virus Qexactive 
TranscriptomicsMicroarray analysis of healthy volunteers that received measles, mumps and rubella vaccination
RNA was extracted from whole blood of subjects collected in Tempus tubes on day 0 (immediately prior to vaccination), day 1 and 3 post-vaccination. We performed gene expression analysis of subjects with similar baseline antibody titres to rubella virus (RV) that experienced an increase in anti-RV Ig...
ORGANISM(S): Homo sapiens 
2019-04-03 | E-MTAB-7055 | biostudies-arrayexpress
ProteomicsIdentification of proteolytic fragments of human hemoglobin
The uploaded data is related to the identification of the antibacterial/antiviral human peptide HBB 12-147 in hemoglobin digestion with Napsin-A
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-12-15 | MSV000086600 | MassIVE
TranscriptomicsUnderstanding transcriptional changes associated with the transition to selfing in Arabidopsis thaliana
RNA-seq reads from the selfing species Arabidopsis thaliana were produced from flowers to study the consequences of the transition from the ancestral state (outcrossing) to the derived state (selfing). This was done in the context of examining another species in the Arabidopsis genus (A. lyrata) and...
ORGANISM(S): Arabidopsis thaliana 
2013-04-02 | E-GEOD-45685 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of immune response in healthy controls and COVID-19 cases using the NanoString Human Immunology Panel
Daily transcriptomic profiling was conducted on whole blood collected from COVID-19 cases. Whole blood was collected in Tempus Blood RNA tubes, and RNA was extracted from whole blood using the Tempus Spin RNA Isolation Kit. Healthy controls consisted of participants of a measles, mumps and rubella r...
ORGANISM(S): Homo sapiens 
2020-03-27 | E-MTAB-8871 | biostudies-arrayexpress
TranscriptomicsDaily transcriptomic profiling of immune response in COVID-19 cases and healthy controls using the NanoString Human Immunology Panel
Daily transcriptomic profiling was conducted on whole blood collected from COVID-19 cases. Whole blood was collected in Tempus Blood RNA tubes, and RNA was extracted from whole blood using the Tempus Spin RNA Isolation Kit. Healthy controls consisted of participants of a measles, mumps and rubella r...
ORGANISM(S): Homo sapiens 
2021-02-24 | E-MTAB-9719 | biostudies-arrayexpress
TranscriptomicsHuman memory T cells of the bone marrow are resting and maintain long-lasting memory
To compare human memory CD4+ T cell subsets in peripheral blood (PB) and bone marrow (BM) of healthy individuals at transcriptional level, we analyzed the global gene expression of ex vivo PB CD69- as well as BM CD69- and CD69+ memory CD4+ T cells from 4 paired PB and BM samples. The gene expression...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-50677 | biostudies-arrayexpress
TranscriptomicsThe consequences of rapid mating system evolution in crucifer genomes
We compare RNA expression and polymorphism patterns between C. rubella and its outcrossing progenitor C. grandiflora. There is a clear shift in the expression of genes associated with flowering phenotypes; a similar shift is seen in the related genus Arabidopsis, where self-fertilization evolved abo...
ORGANISM(S): Capsella grandiflora 
2013-03-28 | E-GEOD-45518 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of IFN-response
Type I interferon (IFN-α/β) is the first line of defense against viral infection. Mouse models have been pivotal to our understanding of IFN-α/β in immunity, although validation of these findings in humans has not been possible. We investigated a previously healthy child with fatal susceptibility to...
ORGANISM(S): Homo sapiens 
2015-06-12 | E-GEOD-67737 | biostudies-arrayexpress
Genomicsf1d65243-e860-4420-af20-d1886b7fe529 - samples
Short Description: This study contains 7 RRBS samples, including 3 ex vivo CD4+ Trm (2 x spleen and 1 x bone marrow) and 4 blood tetanus (TT) and measles (Me) antigen-reactive memory CD4+ cells before and one day post DTaP (diphtheria-tetanus-pertussis) and MMR (measles-mumps-rubella) vaccination, r...
EGAD00001007886 | EGA
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