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ProteomicsPAXX is an accessory c-NHEJ factor that associates with Ku70 and has overlapping functions with XLF
In mammalian cells, classical non-homologous end joining (c-NHEJ) is critical for DNA double-strand break repair induced by ionizing radiation and during V(D)J recombination in developing B and T lymphocytes. Recently, PAXX was identified as a new c-NHEJ core component. We report here, that PAXX-def...
ORGANISM(S): Homo sapiens (Human) 
2016-10-06 | PXD004659 | Pride
Non-homologous end joining Micro-homology mediated end joining V(d)j recombination Genomic instability Dna double-strand break 
UnknownSelective Synthesis of α,α-Difluoro- and α-Monofluoro Methylene Substituted Arenes by Defluoro C-C Bond Coupling.
Not available
S-EPMC12577133 | biostudies-literature
UnknownTri1 encodes the cytochrome P450 monooxygenase for C-8 hydroxylation during trichothecene biosynthesis in Fusarium sporotrichioides and resides upstream of another new Tri gene.
Not available
S-EPMC150100 | biostudies-literature
UnknownTri16 is required for esterification of position C-8 during trichothecene mycotoxin production by Fusarium sporotrichioides.
Not available
S-EPMC201190 | biostudies-literature
UnknownNucleotide signaling pathway convergence in a cAMP-sensing bacterial c-di-GMP phosphodiesterase.
Not available
S-EPMC6717892 | biostudies-literature
TranscriptomicsTransciptional response to acute thermal stress in Chinook salmon
Thermal stress is a serious and growing challenge facing Chinook salmon (Oncorhynchus tshawytscha) living in the southern portion of their native range. River alterations have increased the likelihood that juveniles will be exposed to warm water temperatures during their freshwater life stage, which...
ORGANISM(S): Oncorhynchus tshawytscha 
2015-07-25 | E-GEOD-59756 | biostudies-arrayexpress
UnknownMutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining.
Not available
S-EPMC5468090 | biostudies-literature
UnknownPhase 1 study of romidepsin plus erlotinib in advanced non-small cell lung cancer.
Not available
S-EPMC5125089 | biostudies-literature
UnknownStereoselective Synthesis of Alkenyl Fluorides and Alkynes by Defluoro Coupling of Trifluoromethyl Arenes.
Not available
S-EPMC12636270 | biostudies-literature
UnknownThe ATM Kinase Restrains Joining of Both VDJ Signal and Coding Ends.
Not available
S-EPMC5101155 | biostudies-literature
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