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ProteomicsProteomic validation of MEG-01-Derived Extracellular Vesicles as Biologically Representative Models for Megakaryocyte- and Platelet-Derived Extracellular Vesicles.
Platelets and their extracellular vesicles (EVs) have emerged as promising liquid biopsy biosources for cancer detection and monitoring. The megakaryoblastic MEG-01 cell line offers a controlled system for generating platelet-like particles (PLPs) and EVs through valproic acid induced differentiatio...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD070221 | Pride
Meg-01 cell line Exosomes (exos). Extracellular vesicles (evs) Proteomics Microvesicles (mvs) Platelets 
TranscriptomicsRunx1 (Aml1) knockdown in AMkL Meg-01 cells
Transcriptional profiling of the effect of shRNA silencing of Runx1 in human AMkL Meg-01 cells. RNA samples obtained from two independent colonies were compared to RNAs from negative control transductions in a two-color design. A total of four microarrays were completed, with a dye-swapped pair per...
ORGANISM(S): Homo sapiens 
2009-08-01 | E-GEOD-17311 | biostudies-arrayexpress
GenomicsMeg-01 cell line expression data after propionate stimulation
Meg-01 cell line expression data after propionate stimulation
PRJNA837092 | ENA
TranscriptomicsMeg-01 cell line expression data after propionate stimulation
Platelets are produced by megakaryocytes, deriving from megakaryocyte erythrocyte progenitors (MEP) in the bone marrow. Increased megakaryocyte expansion across common autoimmune diseases was shown for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS)...
ORGANISM(S): Homo sapiens 
2022-05-14 | GSE202712 | GEO
TranscriptomicsIdentification of GATA1 transcriptional regulation in the megakaryoblastic cell line Meg01
chIP-on-chip analysis of GATA1 in the megakaryoblastic cell line Meg01. The IP was obtained with a GATA1 C-terminus antibody. The control sample was a normal goat IgG pull down done side by side with the GATA1 (C-20) antibody using the same soluble chromatin sample from non-treated Meg-01 cells. A ...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-GEOD-43018 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human chronic lymphocytic leukemia samples and pRS-15/16 transfected MEG01 cell lines to identify MiR-15a and miR-16-1 cluster function in human leukemia
Two samples obtained from the MEG01 cell line transfected with pRS-15/16 and pRS-E vector, each one in triplicate, and 16 CLL samples were analyzed by microarray using Human Genome U133A Plus 2.0 GeneChip arrays (Affymetrix).
ORGANISM(S): Homo sapiens 
2008-06-01 | E-MEXP-1482 | biostudies-arrayexpress
UnknownSp1/3 and NF-1 mediate basal transcription of the human P2X1 gene in megakaryoblastic MEG-01 cells.
Not available
S-EPMC1464135 | biostudies-literature
UnknownProteomic Validation of MEG-01-Derived Extracellular Vesicles as Representative Models for Megakaryocyte- and Platelet-Derived Extracellular Vesicles.
Not available
S-EPMC12730508 | biostudies-literature
Genomics
SON siRNA Treatment in MEG-01
PRJNA658257 | ENA
UnknownDengue virus infection impedes megakaryopoiesis in MEG-01 cells where the virus envelope protein interacts with the transcription factor TAL-1.
Not available
S-EPMC7658202 | biostudies-literature
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