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MetabolomicsMulti-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in rats
Health effects of pesticides are not always accurately detected using the current battery of regulatory toxicity tests. We compared standard histopathology and serum biochemistry measures and multi-omics analyses in a subchronic toxicity test of a mixture of six pesticides frequently detected in foo...
2020-11-19 | MTBLS138 | MetaboLights
TranscriptomicsTranscription profiling of human cancer cell lines
We describe a novel approach combining RNAi screening in multiple cell lines with expression profiling to identify novel cancer targets in breast cancer cell lines
ORGANISM(S): Homo sapiens 
2010-03-02 | E-TABM-610 | biostudies-arrayexpress
TranscriptomicsChange in expression of genes after retinoic acid treatment of stellate cells: dose response
We evaluated the change in expression of genes after treatment of stellate cells with retinoic acid to understand how the stellate cells can de-differentiate and effect their physiological behaviour in pathological conditions. We then tested the changes in the gene expression in 2D and 3D culture co...
ORGANISM(S): Homo sapiens 
2011-12-30 | E-GEOD-14425 | biostudies-arrayexpress
TranscriptomicsChange in expression of genes after retinoic acid treatment of stellate cells: time course
We evaluated the change in expression of genes after treatment of stellate cells with retinoic acid to understand how the stellate cells can de-differentiate and effect their physiological behaviour in pathological conditions. We then tested the changes in the gene expression in 2D and 3D culture co...
ORGANISM(S): Homo sapiens 
2011-12-30 | E-GEOD-14426 | biostudies-arrayexpress
GenomicsGenome wide association study of Coeliac Disease
We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS) < 10(-4) and 18 SNPs from 14 known loci in a further 4,918 cases and 5,684 controls. Variants from 13 new regions r...
EGAS00000000057 | EGA
UnknownSomatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production.
Not available
S-EPMC10260400 | biostudies-literature
GenomicsFinnuncorrNLITUK3hap550_onlyNBS - samples
NBS control samples only (Hap550)
EGAD00010000290 | EGA
GenomicsFinnuncorrNLITUK1UK3hap300_onlyNBS - samples
NBS control samples only (Hap300)
EGAD00010000284 | EGA
GenomicsFinnuncorrNLITUK1UK3hap300 - samples
All cases and controls (Hap300)
EGAD00010000298 | EGA
GenomicsFinnuncorrNLITUK1UK3hap300_no1958BC_noNBS - samples
All cases and Finnish, Dutch, Italian control samples (Hap300)
EGAD00010000292 | EGA
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