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ProteomicsElectroneutral polymer nanodiscs enable interference-free probing of membrane proteins in a lipid-bilayer environment
Membrane proteins can be examined in near-native lipid-bilayer environments with the advent of polymer-encapsulated nanodiscs. These nanodiscs self-assemble directly from cellular membranes, allowing in vitro probing of membrane proteins with techniques that had previously been restricted to soluble...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD030958 | Pride
Membrane proteins Dibma nanodiscs 
TranscriptomicsTranscription profiling of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines
Gene expression data of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines for the article: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells Glucocortic...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-22152 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of non-leukemic individuals before and during in-vivo glucocorticoid treatment
Article title: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells. Glucocorticoids (GCs) cause apoptosis and cell cycle arrest in lymphoid cells and constitute a central component in ...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-22779 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood lymphocytes from ALL patients treated with Prednisolone at three time points
Glucocorticoids (GC) are in most chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukaemia (ALL) for their ability to induce apoptosis in malignant blast. The underlying mechanism, however, has so far only been investigated in model systems. This study co...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2677 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human blood lymphoblasts purified at three time points from childhood ALL samples (0h, 6-8h, 24h after treatment with prednisolone
Glucocorticoids (GC) are in most chemotherapy protocols for lymphoid malignancies, particularly childhood acute lymphoblastic leukaemia (ALL) for their ability to induce apoptosis in malignant blast. The underlying mechanism, however, has so far only been investigated in model systems. This study co...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2842 | biostudies-arrayexpress
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