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TranscriptomicsChromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrent.
Background & Aims: The metastatic process is complex and remains a major obstacle in the management of colorectal cancer (CRC). To gain a better insight into the biologic events driving the metastatic process we investigated genomic aberrations in a large cohort of matched CRC primaries and distant ...
ORGANISM(S): Homo sapiens 
2014-02-10 | E-GEOD-38479 | biostudies-arrayexpress
UnknownImproving sustainability of a patient decision aid for systemic treatment of metastatic colorectal cancer: A qualitative study
Not available
S-EPMC11225887 | biostudies-literature
UnknownWatchful waiting for small non-functional pancreatic neuroendocrine tumours: nationwide prospective cohort study (PANDORA).
Not available
S-EPMC10364894 | biostudies-literature
TranscriptomicsGenomic landscape of metastatic colorectal cancer
Response to drug therapy in individual colorectal cancer (CRC) patients is associated with tumor biology. Here we describe the genomic landscape of tumor samples of a homogeneous well-annotated series of patients with metastatic CRC of two phase III clinical trials, CAIRO and CAIRO2. DNA copy number...
ORGANISM(S): Homo sapiens 
2014-11-14 | E-GEOD-36864 | biostudies-arrayexpress
TranscriptomicsBeyond KRAS mutation status: influence of KRAS copy number status and microRNAs on response to cetuximab in metastatic colorectal cancer patients
KRAS mutation is a negative predictive factor for treatment with anti-epidermal growth factor receptor (EGFR) antibodies in metastatic colorectal cancer (mCRC). Novel predictive markers are required to further improve the selection of patients for this treatment. Here, we assessed the influence of m...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-32048 | biostudies-arrayexpress
UnknownImpact of nationwide enhanced implementation of best practices in pancreatic cancer care (PACAP-1): a multicenter stepped-wedge cluster randomized controlled trial.
Not available
S-EPMC7161112 | biostudies-literature
UnknownImplementation of Best Practices in Pancreatic Cancer Care in the Netherlands: A Stepped-Wedge Randomized Clinical Trial.
Not available
S-EPMC10867778 | biostudies-literature
UnknownAutomating tumor-stroma ratio quantification in colon cancer patients from the UNITED study.
Not available
S-EPMC12804037 | biostudies-literature
UnknownThe Prospective Dutch Colorectal Cancer (PLCRC) cohort: real-world data facilitating research and clinical care.
Not available
S-EPMC7887218 | biostudies-literature
UnknownTrends in Use and Perceptions About Triplet Chemotherapy Plus Bevacizumab for Metastatic Colorectal Cancer.
Not available
S-EPMC8433607 | biostudies-literature
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