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MetabolomicsMetabolomics analysis of Sirt5 knockdown (KD) melanoma
Not available
ORGANISM(S): Homo sapiens 
ST000698 | MetabolomicsWorkbench
TranscriptomicsClinical relevance of SKP2 alterations in metastatic melanoma
Melanoma cell lines were genotyped to evaluate copy number differences between nodular melanoma (NM) and superficial spreading melanoma (SSM). Cell lines were also evaluated for copy number alterations in the SKP2/p27 axis. Affymetrix SNP arrays were performed according to manufacturer's instruction...
ORGANISM(S): Homo sapiens 
2010-10-21 | E-GEOD-22305 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human tissue samples to identify novel genes associated with malignant melanoma but not benign melanocytic lesions
A number of melanoma specific genes were identified to differentiate clinical relevant tissue samples containing benign from malignant melanocytes. Experiment Overall Design: 7 normal skin, 18 nevi and 45 melanoma samples
ORGANISM(S): Homo sapiens 
2007-09-06 | E-GEOD-3189 | biostudies-arrayexpress
GenomicsLoss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
DNA methylation at the 5-position of cytosine (5-mC) is a key epigenetic mark critical for varius biological and pathological processes. 5-mC can be converted to 5-hydroxymethylcytosine (5-hmC) by the Ten-Eleven Translocation (TET) family of DNA hydroxylases. Here we report that "loss of 5-hmC&...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-38231 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of different human melanoma cells in response to 5-aza-deoxycytidine
(subset of yale_halaban_skinspore_1) expression analysis in response to 5-aza-deoxycytidine and normal melanocytes versus melanoma.
ORGANISM(S): Homo sapiens 
2010-01-18 | E-MTAB-185 | biostudies-arrayexpress
TranscriptomicsMicroRNA Expression Profiles Associated with Mutational Status and Survival in Malignant Melanoma
In order to improve our understanding of microRNA (miRNA) deregulation in melanoma development and possible consequences for patient survival, miRNA expression profiles were determined, using an array based approach, in melanoma tumors, melanoma cell lines and normal melanocytes. Differentially expr...
ORGANISM(S): Homo sapiens 
2010-04-21 | E-GEOD-19387 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanoma cell lines (63)
63 melanoma cell lines hybridized to Affymetrix Hu133_Plus 2 oligo arrays. The aim of this study was to identify potential downstream targets of key oncogenes and TSGs in melanoma (including p14ARF, p16INK4A, BRAF etc). Publications relevant to this series include:; Johansson et al. Pigment Cell Res...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7127 | biostudies-arrayexpress
MetabolomicsDisruption of Redox Balance Enhances the Effects of BRAF-inhibitors in Melanoma
Not available
ORGANISM(S): Homo sapiens 
ST001339 | MetabolomicsWorkbench
TranscriptomicsAffymetrix expression array data for melanoma progression to the brain
Melanoma is one of the most aggressive and treatment-resistant cancers. It represents the most life-threatening neoplasm of the skin, and its incidence has been increasing for the last three decades. Melanoma evolves from the local transformation of melanocytes to primary tumors, which can metastasi...
ORGANISM(S): Homo sapiens 
2013-09-19 | E-GEOD-44660 | biostudies-arrayexpress
TranscriptomicsExpression analysis of zebrafish melanoma and skin from the mitf-BRAFV600E;p53-/- line
Investigation of expression differences between skin and melanomas from a transgenic BRAFV600E zebrafish model of melanoma The embryos described in this study are further analyzed in a manuscript submitted for publication by White, et al. A 15 chip study using RNA extracted from either WT zebrafish ...
ORGANISM(S): Danio rerio 
2011-03-30 | E-GEOD-24528 | biostudies-arrayexpress
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